CAN ACROCHORDONS BE A MARKER OF METABOLIC SYNDROME?
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 56
Abstract
BACKGROUND Acrochordon or fibroepithelial polyp known as skin tags are one of the most common benign skin conditions. It consists of skin projecting from the surrounding skin usually occurring in the eyelids, neck and axilla. The aetiology of acrochordons is still unknown. They usually vary in diameter and are skin coloured. The incidence of obesity in India is increasing at an alarming rate. Less physical activity amongst both children and adults are leading to it. The aim of the present study is to find out if there is any association of acrochordons with blood glucose, HbA1C, lipid profile and BMI in outdoor patients selected from the Department of Dermatology, Calcutta National Medical College, Kolkata-700014. Ethics committee clearance was obtained from the mother institute. MATERIALS AND METHODS This was a descriptive comparative study with a simultaneous comparison group. The study was done in Calcutta National Medical College, Kolkata-14. A total number of 50 patients with at least 3 skin tags aged 30-50 years and who are not established diabetic were included in the study. 50 individuals aged between 30-50 years whose age and sex was matched with the cases were examined in Dermatology Outpatient Department in Calcutta National Medical College served as comparisons for the study. The fasting blood glucose, HbA1c, cholesterol, HDL, LDL, VLDL, triglyceride levels and BMI (basal metabolic rate) were measured for both study groups. Statistical analysis was done by SPSS Version 16. RESULTS There was significant statistical difference in fasting blood glucose, glycosylated haemoglobin, high-density lipoprotein, lowdensity lipoprotein, very low-density lipoprotein, cholesterol, triglyceride and basal metabolic rate between the study group and the comparison group. The patients’ group showed significantly higher levels of all the above parameters when compared with the comparison group (p value <0.001). CONCLUSION Blood glucose, cholesterol and triglyceride levels should be checked from time to time in patients with skin tags to provide corrective measures in the prevention and further exacerbation in presence of metabolic syndrome.
Authors and Affiliations
Devyani De, Mallika Biswas, Dayamay Pal, Tarun Biswas
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