CAN GARCINIA COCHINCHINENSIS CHOISY AFFECT FOOD INTAKE AND BEHAVIOR IN EXPERIMENTAL MODELS?
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12
Abstract
Studies have demonstrated an intrinsic relationship between obesity and anxiety, highlighting anxiety as both a frequent symptom among the obese and its strong relationship with an increase in food consumption. The objective of this study was to evaluate the effects of the consumption of the fruit and leaves from Garcinia cochinchinensis Choisy, the fruit known as yellow mangosteen, on the food intake and behavior of Wistar rats. 24 animals were used, divided into a control group (G1=8), which received water ad libitum, the G2 group (n=8) treated with juice from the pulp (40%), and the G3 group (n=8), treated with juice from the leaves (40%) of the fruit. After 40 days of experiment, behavioral analyses were carried out using the open field and elevated plus maze models, in addition to determining the weight of the animals' visceral fat. The data analysis was performed using analysis of variance (ANOVA) and Tukey's Test, using the SISVAR software and a significance level of 5% probability (p < 0.05). The results revealed a significant reduction in the visceral fat of the animals treated with the yellow mangosteen pulp and leaves compared to the control group. The juices didn't have any effect on the behavior of the animals in the experimental models used. The results of this study can be used as reference for future works on this exotic fruit.
Authors and Affiliations
Flavia Maria Vasques Farinazzi-Machado
Keywords
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