Can Preoperative Haematological Parameters Predict Pathology Results in Patients Undergoing Open Prostatectomy Due to Benign Prostatic Hyperplasia? A Retrospective Study
Journal Title: Meandros Medical and Dental Journal - Year 2021, Vol 22, Issue 1
Abstract
Objective: Although the incidence of incidental prostate cancer (IPCa) has decreased in patients undergoing open prostatectomy with the increasing use of prostate-specific antigen (PSA), cases of IPCa are still reported. This study aimed to investigate the rate of IPCa in our patients who underwent open prostatectomy and to find the relationship between haematological parameters and pathology results. Materials and Methods: Data of patients who underwent open prostatectomy in our urology clinic between January 2014 and December 2019 were retrospectively investigated. Patient age, preoperative PSA level, prostate volume, post-void residual urine volume, history of urethral catheterisation, presence of accompanying bladder stones, pathology results of prostate biopsy, post-operative pathology results, haematological parameters, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were evaluated. Results: A total of 83 male patients were included in the study. The mean patient age was 68.89±6.72 years. The mean preoperative PSA value was 7.46±6.23 ng/mL. Benign prostatic hyperplasia was detected in the post-operative pathology results of all patients; however, prostate adenocarcinoma was found in six (7.2%) and chronic prostatitis accompanied with benign prostatic hyperplasia was detected in 46 (55.4%) patients. PLR and NLR were higher in patients with IPCa than in patients without IPCa. The difference was statistically significant in terms of PLR (p=0.010). By contrast, the mean lymphocyte count was significantly lower in patients with IPCa than in those without IPCa (p=0.009). Conclusion: This study showed that the rate of IPCa in our clinic was similar to that in literature. Results suggest that evaluation of preoperative haematological parameters in patients who underwent open prostatectomy may guide urologists and pathologists in predicting pathological conditions.
Authors and Affiliations
Ahmet Güzel
Keywords
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- EP ID EP693426
- DOI 10.4274/meandros.galenos.2021.32659
- Views 90
- Downloads 0
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