CANCER DU SEIN CHEZ LA FEMMEGE : EXPERIENCE DU SERVICE DONCO-RADIOTHRAPIE CHU DE MARRAKECH BREAST CANCER IN ELDERLY WOMEN: EXPERIENCE OF THE SERVICE OF ONCO-RADIOTHERAPY UNIVERSITY HOSPITAL OF MARRAKECH.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 5
Abstract
Our objective was to analyze the epidemiological, clinical, therapeutic and prognostic of breast cancer in older women. We performed a retrospective study of 35 cases of breast cancer among older women treated and followed in the oncology radiotherapy department of the University Hospital Mohammed VI Marrakech, in over a period of 5 years from 2012 to 2016.Among 603 women who had breast cancer during the study period, 35 were aged 65 and over, or 5,8 %. The average age of these patients was 72-year-old. The mean time for diagnosis was 15 months. A breast nodule was the main sign in 91,42% of cases, associated with inflammatory signs in five cases. The majority of tumors were classified T3 (51,43%) forms classified T4 represented 25,42 % of the tumors. Ipsilateral axillary lymph nodes found in 14 patients or 40 % of cases. The disease was metastatic at diagnosis in 5 cases. Infiltrative ductal carcinoma represented 88,57%. It was in 74,28% of cases of grade II Scarff-Bloom and Richardson (SBR), and 25,72% grade III. The lymph node was positive in 22 patients(62,85%). The expression of HR was noted in 74,28% of cases. HER2 was over expressed in 14,28% of cases. Surgical treatment was performed after neo adjuvant chemotherapy in 7 cases of locally advanced cancers, three patients underwent conservative treatment, while 31 patients underwent a mastectomy with lymphnode dissection, associated with radiation therapy in 77,14% of cases and a profit analgesic radiotherapy in 2 patients. Adjuvant Chemotherapy was prescribed for 20 patients. 74,28% of the patients received hormonal therapy. Trastuzumab was given in 11,42% of cases. The evolution was marked by a complete remission after a decline of a year in 20 cases, 5 patients had progressive disease after a mean of ten months. Conclusion: The age factor is not to be alone a criterion for treatment decisions, understanding the multiple facets of the physical and psychological health of the patient and the medical, social and family should be taken into account.
Authors and Affiliations
N. Bouzid, K. diakit A. Elomrani, M. Khouchani.
Keywords
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- EP ID EP296949
- DOI 10.21474/IJAR01/7103
- Views 64
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