Carcinoma Ovary Masquerading as Metastatic Hepatocellular Carcinoma—Case Report
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2017, Vol 7, Issue 11
Abstract
Malignant tumours with hepatoid features resembling hepatocellular carcinoma (HCC) have been described in different sites. These tumours are very rare and are found particularly in the stomach, ovary, pancreas, renal pelvis and urinary bladder. Hepatoid variant of carcinoma ovary was first of all reported by Isikura and Scully in 1987. Till date, with the best of our knowledge, only 21 patients with diagnosis of Hepatoid carcinoma of the ovary have been reported. No case has been reported from India till date. This is a case of 56 years female presented to us with a complaint of abdominal distension, pain and weight loss of 2 months duration. Omental Biopsy was suggestive of HCC. On IHC, tumour cells were positive for HepPar 1, Glypican 3 and focal positivity for CK7 while negative for SALL4, PAX8, CK20 and TTF 1. She underwent interval cytoreductive surgery in January 2014. The final HPE report was hepatoid variant of carcinoma ovary.
Authors and Affiliations
Amitabh Kumar Upadhyay, Chandragouda Dodagoudar, Pankaj Goyal, Rakesh Gupta, Vijay Jagad
Keywords
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