Cardiac biomarker detection based on nanostructured biosensors
Journal Title: Journal of Medical and Scientific Research - Year 2018, Vol 6, Issue 1
Abstract
Early and accurate detection of plasma borne cardiac biomarkers is essential for prevention of life threatening acute myocardial infarctions. Development of low cost and point of care platforms that can ensure ultrasensitive detection of cardiac biomarkers is key to this endeavor. In this context, herein, a brief discussion is provided highlighting the contribution of nanotechnology and microfabrication towards the development of such biosensing platforms, targeting the detection of several cardiac biomarkers such as Myoglobin, Troponin T, Troponin I and creatine kinase MB. Furthermore, the challenges associated with the conventional techniques that led to the development of the ultrasensitive biosensors are described in brief. In addition to several prominent nanoscale sensors that ensure very low limit of detection of cardiac biosensors, performance analysis of a conductive nanofiber based cardiac biomarker detection platform developed by our team is presented in this paper.
Authors and Affiliations
Shiv Govind Singh, Suryasnata Tripathy
Keywords
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- EP ID EP590767
- DOI 10.17727/JMSR.2017/5-13
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