CARDIAC DYSFUNCTION IN PATIENTS WITH HYPOTHYROIDISM IN ADULTS
Journal Title: INTERNATIONAL JOURNAL OF ADVANCED MEDICINE - Year 2018, Vol 2, Issue 1
Abstract
BACKGROUND: Hypothyroidism is a graded disorder and its cardiovascular effects need further exploration. METHODS: In this prospective case control study, we evaluated, 50 newly diagnosed hypothyroid patients and 25 age and sex matched controls, attending a tertiary care centre of North India for cardiac dysfunction. Statistical analysis was done using SPSS (statistical package for social sciences) software. RESULTS: Hypothyroid patients had signicant dyslipidaemia than controls. Though, the in-group difference for 10-year ASCVD risk score was statistically insignicant (4.81 ± 5.75 vs 3.66 ± 3.50; p = 0.36). On echocardiography, Interventricular septal wall thickness and Left ventricular posterior wall thickness and LVEDD were signicantly increased. Also, signicant number of patients had Diastolic Dysfunction, mean E/A ratio (0.90 ± 0.16 vs 1.02 ± 0.10; p = 0.001). No signicant LV Dysfunction or RWMA was noted. CONCLUSION:The cardiovascular changes and dyslipidaemia were more marked in hypothyroidism compared to controls.
Authors and Affiliations
Dr. Nitnav Bhatnagar, Dr. S. P. Singh, Dr. Amit Varma, Dr. Kiran Bhatt
Keywords
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