Case Report of Hailey-Hailey Disease Successfully Treated with Topical Roflumilast 0.3% Cream
Journal Title: Journal of Dermatology Research - Year 2024, Vol 5, Issue 1
Abstract
Hailey-Hailey Disease, also called Benign Familial Pemphigus, is a genetic acantholytic blistering condition that most commonly affects the intertriginous areas. There are many treatments, both on and off label, for the treatment of this life-long, uncomfortable condition. More efficacious treatments are needed. We believe we are the first to report successful treatment with topical roflumilast, a PDE-4 inhibitor. This helps us to further understand and speculate beyond the genetics, other mechanisms of action that trigger this disease.
Authors and Affiliations
Edward M Klepper1*, Cindy N Mashima1, Tahreem Riaz1, Ahmed Sikder1, Jon R Christofersen Jr1, Samira Vuchula1, Athena G Claudio1, Rista Upadhyay1, Jonathan J Lee2, Howard N Robinson1
Keywords
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- EP ID EP727320
- DOI https://doi.org/10.46889/JDR.2024.5103
- Views 42
- Downloads 0
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