“CELL PROLIFERATION BIOMARKER (KI-67) PROFILING: EFFECT OF GREEN TEA EXTRACT AND BLACK GRAPES ON BREAST TUMORS IN WISTAR RATS”
Journal Title: INTERNATIONAL JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH - Year 2014, Vol 2, Issue 5
Abstract
The Ki-67 protein, measured with immunohistochemical techniques, is a useful marker of cell proliferation in cancer. Ki-67 is an early predictor of treatment efficacy and as a prognostic factor of long term outcome. Ki-67 is frequently measured as a static marker of proliferative activity. The expression of Ki-67 varies in intensity throughout the cell cycle. Ki67 expression is usually estimated as the percentage of tumor cells positively stained by the antibody, with nuclear staining being the most common criterion of positivity. Currently, image analysis techniques will enhance the precision of assessment.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP293457
- DOI -
- Views 94
- Downloads 0
ENHANCING DENTIST’S RESPONSIVENESS TOWARDS DOMESTIC VIOLENCE - A STUDY IN CHENNAI CITY
BACKGROUND: A dentist is the first health care professional to treat patients who have experienced oro -facial trauma resulting from a domestic violence. Hence, it challenges the social responsibility of a dentist in add...
HISTOLOGICAL AND IMMUNOHISTOLOGICAL CHANGES DURING THE EXPRESSION OF FOXO3A IN HUMAN BREAST CANCER TISSUES
Background & Objectives: Breast cancer is an aggressive cancer in females, worldwide and is the major cancer among Indian women. The cause of breast cancer includes environmental, genetic and hormonal factors. The presen...
SERUM ASCITIC ALBUMIN GRADIENT & ASCITIC FLUID CHOLESTEROL - NEWER APPROACH TO EVALUATE ASCITES
Ascites is common clinical condition. The underlying pathogenesis involves various mechanisms. In present study we had investigated 100 cases of ascites with regard to clinical history, biochemical parameters & cytologic...
A COMPARATIVE EVALUATION OF THE ANTI-ULCER ACTIVITY OF THE EXTRACTS OF SEED AND SKIN OF VITIS VINIFERA (GRAPE) IN WISTAR ALBINO RATS
Background: Peptic ulcer disease is a most common disease, whose incidence is increasing presently on account of demanding stressful life. Objectives: To evaluate and compare the antiulcer activity of the extracts of see...
SERUM FERRITIN, A NOVEL RISK FACTOR IN ACUTE MYOCARDIAL INFARCTION
To test whether excess body iron stores as estimated by serum ferritin concentration is associated with increase in risk of Myocardial Infarction and to evaluate the role of ferritin as an oxidant. Total 75 cases and an...