Cementum: Composition, Formation and Regeneration
Journal Title: Journal of Clinical Medical Research - Year 2022, Vol 3, Issue 1
Abstract
Cementum is forming a thin layer over the root. Incremental lines of Salter reflect periodic deposition, separating mixed cementum into successive layers. Cementum plays a role in the anchorage of the teeth and adaptative, reparative and regenerative functions. Entrapped in cementum, cementoblasts become cementocytes located inside lacunae. Type I (90%) and III (5%) collagens constitute the major components of the matrix. In addition, non-collagenous proteins include proteoglycans, bone sialoprotein, osteopontin, fibronectin, osteonectin, a2-HS glycoprotein (also named fetuin-A), osterix and non-specific alkaline phosphatase (NSAP). It contains also cementum-specific proteins, a number of growth factors (IGF, FGF, PDGF, TGF b, BMPs and EGF), transcription factors, enamel-associated proteins and tuftelin, involved in the initial stages of enamel mineralization. These molecules contribute to cementum formation, structural and molecular repair and may be used for cementum regeneration.
Authors and Affiliations
Michel Goldberg1*
Keywords
Related Articles
- EP ID EP700569
- DOI http://dx.doi.org/10.46889/JCMR.2022.3104
- Views 96
- Downloads 0
Characterization the Teenage Students from the Schools “Boris Luis Santa Coloma” and “Seguidores de Camilo” in Risk about the Drug Consumption
Background: Teenage people should be sensible to the drugs consumption. This attitude often is related with personal and social problems. This is a multi-social problem present for the Public health, education and fami...
Nanoparticles in Peritoneal Carcinomatosis
The management of peritoneal metastasis remains controversial. The logo regional treatments are Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and recently the Pressurized Intraperitone...
Potential Risk Factors of Glioblastoma Multiforme in Greek Adults: A Case- Control Study
Aim: The aim of the current report was to assess the association between potential risk factors in the pathogenesis of Glioblastoma Multiforme (GBM) in a Greek adult sample. Materials and Methods: The study sample cons...
Magnitude and Factors Associated With Acute Malnutrition among 6-59 Months Old Age Children Dire Dawa and Erer Towns of Eastern Ethiopia, 2021
Background: Children are most vulnerable to malnutrition in developing countries because of low dietary intake, lack of appropriate care and inequitable distribution of food within the household. Both moderate and seve...
Comparison of Functional Echocardiographic Markers in Septic and Non-Septic Neonate
Background: Neonatal sepsis accounts for significant morbidity and mortality and its hemodynamics is complex. Functional echocardiography is emerging at a rapid pace and currently it is considered as a key tool for provi...