Comparison of Functional Echocardiographic Markers in Septic and Non-Septic Neonate
Journal Title: Journal of Clinical Medical Research - Year 2024, Vol 5, Issue 3
Abstract
Background: Neonatal sepsis accounts for significant morbidity and mortality and its hemodynamics is complex. Functional echocardiography is emerging at a rapid pace and currently it is considered as a key tool for providing real time information on cardiovascular performance. Objective: To assess and compare functional Echocardiographic markers in septic and non-septic neonate. Methodology: This cross-sectional comparative study was conducted in the Department of Neonatology, BSMMU over an Eighteen-month period from March 2022 to August 2023. 25 neonates including term baby and preterm ≥ 34 weeks with early or late-onset sepsis satisfying the inclusion criteria were enrolled for the study and compared with same gestational age matched healthy control. Result: Comparison of functional echocardiographic parameters between two groups were statistically significant in respect to right and left ventricular output and tricuspid annular plane systolic excursion. Cardiac output was increased (rt. ventricular output 277.4 ± 74.2 Vs 209 ± 70, lt. ventricular output 339.5 ± 43.2 Vs 276 ± 74.9, p-values were 0.002 and 0.001 respectively) and tricuspid annular plane systolic excursion (0.49 ± 0.13 Vs 0.74 ± 0.34, p value 0.001) was decreased in septic neonate compared to healthy counterpart. The result was also statistically significant result in respect to right and left ventricular output and tricuspid annular plane systolic excursion (p-values were 0.039, 0.004 and 0.01) respectively in comparison between preterm septic and non-septic newborn. When compared between the term neonates (37 weeks to 40 weeks) of both groups, there were also statistically significant result in respect to right ventricular output, left ventricular output and tricuspid annular plane systolic excursion (p- values were 0.006,0.03 and 0.025) respectively. Conclusion: Significant cardiovascular changes like cardiac output and right ventricular systolic dysfunction evidenced by Functional Echocardiography, were common association of neonatal sepsis in comparison to non-septic neonate.
Authors and Affiliations
Ferdous Jahan1, Md. Arif Hossain2, Atikur Rahman3, Rumpa Mani Chowdhury4, Ismat Jahan5, Mohammad Kamrul Hassan Shabuj6, Sadeka Choudhury Moni7, Sanjoy Kumer Dey8, M Shahidullah9, MA Mannan10*
Keywords
Related Articles
- EP ID EP750277
- DOI https://doi.org/10.46889/JCMR.2024.5310
- Views 2
- Downloads 0
Pilot Study on Psychophysiological Characteristics of Occupational Burnout Syndrome among Various Medical Specialists
Introduction: Burnout syndrome is a real scourge of the XXI century, especially for people who work within a communication-related field. However, the issues on development and specific manifestations of occupational s...
A Case of Pregnant Woman with Severe Mitral Regurgitation Demonstrating Left Ventricular Non-compaction
Left ventricular non-compaction is a rare form of cardiomyopathy. It is characterized by a thin compacted epicardial layer and a noncompacted endocardial layer with significant wall trabeculations and intertrabecular rec...
The Study of Relationship between Plasma Fibrinogen Level and the Macrovascular Complications in Type 2 Diabetes Mellitus patients in a Tertiary Health Care Centre in Eastern India
Introduction: The macrovascular complications in patients of Type 2 Diabetes Mellitus (T2DM) are an expression of the generalized atherosclerotic process affecting the blood vessels of the body. Studies have revealed car...
Scaffolds Combined with Stem Cells have Synergistic Effect in Regenerative Dentistry
Tissue engineering generates alternatives for tissues regeneration and/or reconstructive surgery. Materials and fabrication technologies are important in designing temporary extracellular matrices (scaffolds), implicat...
ChatGPT/AI in Healthcare Management
ChatGPT is forging a revolution in the realm of human-computer interaction, establishing new paradigms for what artificial intelligence can achieve. Also known as the Generative Pretrained Transformer (GPT), ChatGPT repr...