Central Corneal Thickness – A Must In Management of Glaucoma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Purpose: To determine the correlation of central corneal thickness (CCT) with intraocular pressure measurement (IOP) & to reclassify the patients of Primary Open Angle Glaucoma (POAG), Normal Tension Glaucoma (NTG) & Ocular Hypertension (OHT) based on their corrected IOP. Design: Retrospective analysis. Material & Methods: It was a retrospective non- interventional, observational study. 100 cases & 20 controls were inducted in the study. Central corneal thickness was measured by ultrasonic pachymeter. Corrected IOP was calculated based on CCT value (correction factor of 3.0mm Hg for every 50µm of difference from 550µm) using a linear formula Corrected IOP = Measured IOP – (CCT – 550)/50 x 3.0mm Hg. Results: Total of 100 cases (POAG -54, NTG- 26 & OHT- 20) & 20 controls were included in the study. There was no significant difference in CCT between controls and patients with POAG but the CCT in the group with NTG was significantly lower than that in the control group or the group with POAG (P<.001), and the CCT in the group with OHT was significantly higher than in controls or patients with POAG (P<.000). There was significant difference in IOP values in NTG & OHT cases when CCT correction was taken in measuring the IOP (p value<0.000) Conclusion: Patients with NTG have a thinner CCT than do patients with POAG or controls. Correcting IOP for corneal thickness, 42% of the patients with NTG could be reclassified as having POAG, and 30% of the patients with OHT as normal and 13% of POAG cases were actually found to be cases of NTG
Authors and Affiliations
Dr Sankalp Seth, Dr Gaurav Kapoor, ,Dr Vijay Mathur, Dr Deepti Sahran
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