CERVICAL DYSPLASIA RISK IN MULTIPLE SCLEROSIS PATIENTS
Journal Title: Kocatepe Medical Journal - Year 2023, Vol 24, Issue 4
Abstract
OBJECTIVE: In this study, we aimed to investigate the relationship between Multiple Sclerosis (MS) disease and the development of cervical dysplasia. MATERIAL AND METHODS: This is a retrospective case-control study that included 262 patients, 62 patients aged 18-65 years and 200 control group, who were followed up in a tertiary health center for MS disease. For the study, the primary outcome measure was to determine the frequency of cervical dysplasia in MS patients and to determine whether MS disease had an effect on Pap smear results. The secondary outcome measure was to determine the relationship between immunomodulatory and immunosuppressive treatment, two different types of treatment used for MS disease, and disease duration, with Pap smear results. RESULTS: The difference between Pap smear results between MS patients and control group was not significant (p=0.938). In MS patients and control group, the most common Pap smear test result was found as inflammation (MS group: 61.9%; control group: 63%). Difference between Pap smear results between patients using immunomodulator and immunosuppressor drugs for MS treatment was not significant (p=0.988). Age and drugs used did not predict the Pap smear result (p=0.316). CONCLUSIONS: In MS patients, the most common Pap smear change is inflammation. More studies are needed to understand the relationship between the duration of the disease and the type of medication used in treatment and Pap smear results.
Authors and Affiliations
Özlem KAYACIK GÜNDAY, Gökçe ZEYTİN DEMİRAL, Şerafettin BAYSAL, Tacettin SEVİM, Selin YOLDAŞ, Berkay ÇELEBI, Ensar ÇAM
Keywords
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- EP ID EP722689
- DOI 10.18229/kocatepetip.1230125
- Views 47
- Downloads 0
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