Cervical Smear Screening Using Cost-effective Liquid Based Cytology
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 6
Abstract
Objective: To minimise false negativity in cervical cancer screening with Papanicolaou (Pap) test, there is a need to explore novel cytological technique and identification of unique and important cellular features. Method: The present study explores the feasibility of low cost cervical monolayer in comparison to conventional Pap smear and available liquid based cytology techniques in extracting cytopathological features to classify normal and abnormal conditions. Comparative efficacy of newly developed technique to that of commercially prepared one was validated by automated cellular image analysis. Result: The results show that newly developed monolayer technique for cervical smears was cost effective, capable of better cyto-pathological evaluation and also compatible for automation. The precision and sensitivity were remarkably improved for nucleus and cytoplasm using cost effective monolayer in comparison to other available techniques. Conclusion: The proposed cost-effective monolayer technology could increase the efficiency of the cervical screening to a greater extent thereby reducing the rates of faulty diagnosis
Authors and Affiliations
Lopamudra Das
Keywords
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