Challenges of Childhood Uveitis
Journal Title: Sultan Qaboos University Medical Journal - Year 2009, Vol 9, Issue 3
Abstract
Chronic uveitis is a rare, but potentially sight-threatening disease. Te most common cause of chronic non-infectious uveitis is “idiopathic uveitisâ€. However, some systemic diseases are associated with chronic uveitis in children and are discussed. Chronic uveitis merits special consideration in children. Te unique differences in children are highlighted with special consideration for the diagnostic and therapeutic challenges encountered in their management. While corticosteroids remain the mainstay of initial therapy, a wide range of immunosuppressive agents have been used with variable success. Te role of immonomodulatory agents such as methotrexate, cyclosproin and some of the new biologic agents such as etanecept, infliximab, adalimumab are reviewed. Successful outcomes may be achieved with appropriate immunosuppressant therapy when given early in the disease, although clinical trials are required to defne the true efcacy of this strategy.
Authors and Affiliations
Reem Abdwani| Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
Keywords
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