Change in weight and morphology of adrenal gland in cases of alleged suicidal deaths: A prospective study 1Preet Inder Singh, 2Ajay Kumar, 3Amandeep Singh, 4RPS Punia, 5Dasari Harish
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
Introduction: The adrenal gland consists of two parts, one is adrenal medulla which constitutes around 28 % of total mass of adrenal gland, and rest is known as adrenal cortex. The average weight of adrenal gland in healthy adults is around 4 g. Aims & objective: In the present study weight and morphology of adrenal gland were studied and comparison between findings in suicidal deaths and non suicidal deaths was done. Material and methods: The adrenals were collected from dead bodies brought for medico-legal autopsies conducted by the department of Forensic Medicine and Toxicology from Dec. 2015 to Sep. 2017. After removal, the weight of the gland was recorded, and then the gland collected was preserved in 10 % formalin for more than 2 weeks for fixation. After the period of fixation, grossing of gland was done and slides were prepared and studied. Results: In study group, maximum weight of left adrenal gland was 6.2 grams and minimum was 4.2 grams while the maximum weight of right adrenal gland was 5.8 grams and minimum was 4 grams. In control groups, maximum weight of left adrenal gland was 5.5 grams and minimum was 3.9 grams and the maximum weight of right adrenal gland was 5.1 grams and minimum was 3.8 grams. There was a positive correlation between the weight of adrenal gland in suicidal group and control group (SD- 0.43, p=0.00). Also, in suicidal group, weight of left adrenal gland was more than the right adrenal gland and was statistically significant. Morphologically, in study group, 2 revealed significant pathological finding of medullary adrenalitis and adrenal abscess. In control group, 4 revealed significant finding of medullary adrenalitis, chronic adrenalitis and pheochromocytoma.
Authors and Affiliations
Dr Amandeep Singh
Keywords
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