Change of Capillaroscopy Data in Patients with Type 1 Diabetes Mellitus in Case of Chronic Complications
Journal Title: Міжнародний ендокринологічний журнал - Year 2014, Vol 2, Issue 58
Abstract
The aim of this work was to study the relationship of capillaroscopy indicators of the upper extremities vessels with the severity of nephropathy, retinopathy, clinical manifestations of angiopathy of lower extremities in patients with diabetes mellitus type 1. Methods of the Study. We examined 53 patients with type 1 diabetes mellitus: 30 females and 23 males. The investigated persons were divided into 3 groups. The computer capillaroscopy was performed to all patients. Results of the Study. The greatest changes of microvasculature were observed in patients of group III, who had marked microangiopathy stages. Defeat of microvasculature of the upper extremities progressed with the development of the underlying disease and manifested by shortened length of capillaries, decreased density of the capillary network, increased diameter of the capillary transition departments. A density of the capillary network is most clearly characterized the state of blood flow, and its decrease indicated profound violations of microcirculation in the periphery. Decrease in the density of the capillary network had a direct correlation with glomerular filtration rate (ρ = 0.601) and inverse correlation with the presence of protein in the urine (ρ = –0.644). In patients with diabetes mellitus type 1 changes in the structure of the capillaries of the nail bed of the upper extremities progressed synchronously to stages of retinopathy and clinical manifestations of angiopathy of lower extremities.
Authors and Affiliations
Ye. S. Krutikov, V. A. Zhitova, M. S. Krutikova
Keywords
Related Articles
- EP ID EP226833
- DOI -
- Views 72
- Downloads 0
Correction of Psychoemotional State in Pregnant Women with Diffuse Toxic Goiter According to Minnesota Multiphasic Personality Inventory
Using Minnesota Multiphasic Personality Inventory, we have examined 50 pregnant women with diffuse toxic goiter of first and the second stage in the second trimester of pregnancy, before and after combined therapy. Studi...
Comparison of Infertility Causes Structure in Men and Women in Tashkent and Andijan Regions of Republic of Uzbekistan According to Screening Data
The structure of the causes of infertility has been studied in 100 couples (200 people) with infertility in Tashkent and Tashkent region (50 families in each). It is found that among surveyed women in the genesis of infe...
State of Left Ventricular Systolic and Diastolic Function in Patients with Postinfarction Cardiosclerosis and Obesity
Cardiovascular diseases are one of the major causes of mortality worldwide, the main contribution to its structure belongs to ischemic heart disease. One of the major factors for the progression of ischemic heart disease...
Questions and Approaches to the Choice of Surgical Treatment of the Differentiated Thyroid Cancer
The differentiated thyroid carcinomas (papillary and follicular) are characterized by very favorable prognosis — the survival of patients exceeds 90 %. At the same time, tactics of their treatment is rather aggressive —...
Nuances of insulin therapy in the treatment of the diabetic ketoacidosis
Background. The well-defined program of the insulin therapy is a guarantee of efficient treatment of a patient with the diabetic ketoacidosis. The approaches to the treatment varied depending on the gained experience, ho...