Changes in corneal scleral rigidity and corneal thickness at various target intraocular pressures in patients with stabilized primary open-angle glaucoma
Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 3
Abstract
Introduction. Current methods for determining target IOP have disadvantages. Investigation of data on corneoscleral rigidity and corneal thickness in patients with stabilized primary open-angle glaucoma of stages I-II may improve the method of determining target IOP. Purpose. To study the correlation between indices of corneoscleral rigidity, corneal thickness and target IOP in patients with stabilized primary open-angle glaucoma (POAG) of stages I-II. Material and Methods. 30 patients (30 eyes) with stabilized POAG of the І-ІІ stage were examined. The patients underwent pachymetry, applanation tonometry, dynamic contour tonometry, corneal rigidity determination and tonography. The progression of glaucoma was monitored by the HFA II Central 30-2 Threshold Test and SOCT Copernicus + units. Target IOP was calculated taking into account the age and the level of diastolic blood pressure. Results. It was found that, in group 1 with target IOP of 6.2 -13.9 mm Hg, the corneal thickness was 540-590 μm and rigidity of the cornea ranged from 1.0 to 4.0 mm Hg; while in group 2 with target IOP of 14.0 -16.8 mm Hg, the corneal thickness was 510-570 μm and rigidity of the cornea ranged from -3.0 to 1.5 mm Hg. Conclusions. It was found that the lower a value of achieved target IOP, the higher corneal rigidity in patients with stabilized stage I-II POAG.
Authors and Affiliations
O. Peretyagin, S. Dmitriev, u. Lazar Y, Yu. Tatarina
Relationship of the AKR1B1 rs759853 and rs9640883 with the development of diabetic retinopathy
Background: In type 2 diabetes mellitus (DM2), hyperglycemia activates the polyol pathway of glucose metabolism, resulting in accumulation of sorbitol and fructose. Polymorphism of aldose reductase (a key enzyme of the p...
Targeted transscleral laser photocoagulation of the ciliary body in patients with neovascular glaucoma
Transscleral laser photocoagulation of the ciliary body is used to reduce intraocular pressure (IOP) in neovascular glaucoma, which is associated with a risk of complications. Purpose. To study the efficacy and safet...
On the scientific results of the 3rd Global Pediatric Ophthalmology Congress (London 2018) and on the effectiveness of publishing articles in high-ranked ophthalmology journals
In this day and age of information technology and significantly accelerated scientific and technical progress in all fields of knowledge including ophthalmology, it is crucial for scientific results obtained to be publis...
Intraoperative changes in intraocular temperature during vitrectomy procedures with irrigating solutions differing in temperature
Background: Intraoperative intraocular media and irrigation fluid temperature monitoring is not performed during vitreoretinal surgery in current clinical practice. Purpose: To investigate intraoperative changes in intr...
Effect of Silicone Hydrogel Contact Lenses on Stability of Cellular and Intracellular Membranes in Corneal Epithelium
Introduction. Contact lenses are increasingly used worldwide for correcting refraction disorders. However, contact lenses can destroy a biochemical composition of the tear. Purpose. To determine the effect of silicone h...