Changes of blood routine parameters in elderly apheresis platelet donors
Journal Title: Chinese Journal of Blood Transfusion - Year 2022, Vol 35, Issue 11
Abstract
Objective To analyze the changes of blood routine and platelet related parameters of the elderly apheresis platelet donors since the first donation, so as to ensure the health and platelet quality of the elderly apheresis donors. Methods From 2019 to 2021, a total of 69 apheresis platelet donors in our center, aged 55-60 years old, involving 3400 occasions of donation, were enrolled in this study. The change trends of blood routine and platelet related parameters before and after the age of 55 were retrospectively analyzed. One way ANOVA was used for group comparison, and Pearson correlation analysis of platelet parameters was performed. Results The values of blood routine and platelet related parameters were higher in men than in women (P<0.05) when stratified by ages. As for the females in comparison of the parameters before 55 years old, RBC, WBC, Hb and Hct after 55 years old decreased significantly (P<0.05), while the platelet parameters of PDW, MPV and P-LCR elevated (P<0.05), and Plt remained unchanged (P>0.05). As for the males in comparison of the parameters before 55 years old, WBC decreased significantly after 55 years of age (P<0.05), while the platelet parameters of PLT, PDW, MPV and P-LCR elevated(P<0.05), and RBC, Hb and Hct remained with no statistical differences (P>0.05). The changes of PDW, MPV and P-LCR were consistent and showed a linear positive correlation. Conclusion The blood routine tests of the elderly apheresis platelet donors were all within the normal range and the proportion was relatively stable. Personalized blood donation schemes should be customized for the elderly blood donors and the health management of blood donors should be implemented.
Authors and Affiliations
Chang TAN, Xin CUI, Yuan ZHOU
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