Changes Of Serum Cardiac Markers After Acute Attack Of Mi Viz. Troponin I, Ck-Mb, Ldh & Hs-Crp
Journal Title: International Journal Of Research In Medicine - Year 2016, Vol 5, Issue 4
Abstract
BACKGROUND: Blood testing for biomarkers of myocardial injury plays an important role for the evaluation, diagnosis, and triage of patients with chest pain. The criteria for the diagnosis of myocardial infarction have been redefined recently, as reported in a document of the European Society of Cardiology (ESC) and the American College of Cardiology (ACC), and require at least 2 of the 3 following characteristics: 1typical symptoms; 2characteristic rise-and-fall pattern of a cardiac markers or 3a typical electrocardiogram (ECG) pattern involving the development of Q waves. Currently serum troponins, can now detect extremely small amounts of my necrosis (<1.0 g), which, in the setting of an ACS, may be associated with increased risk of complications. MATERIALS AND METHODS: Patients are selected from those attending department of medicine, G.G. Hospital, M.P. Shah Medical College, Jamnagar. Blood samples of patients were taken to measure the serum LDH, Troponin I, CRP, CK-MB levels by ELISA (enzyme linked immunosorbent assay) and their levels are compared with clinical condition, ECG changes and prognosis of the patients. RESULT: Out of 100 patients studied 70 patients were in age group 40-70yrs, 74 patients were having history of hyper tension and 55 patients were having complaint of chest pain were diagnosed as having acute MI. CONCLUSION: Troponins are ideal markers which enable early detection of patients with acute coronary syndrome whereas inflammation markers are helpful in diagnosis and assessing the severity of inflammation.
Authors and Affiliations
Charmi Vyas, Shweta Upadhyay ,Mayur Kavar
Keywords
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