Changing trends in histopathology of lung cancer in a tobacco prevalent area of South India
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 2
Abstract
Background Lung cancer is the most devastating disease of mankind among all cancers in the world with 18 million cases In the west adenocarcinoma of lung is the most common type accounts for 385 followed by squamous 23 and large cell carcinoma In India squamous cell carcinoma was common until few recent studies which described the changing trends Present study is done at a tertiary care hospital where tobacco cultivation and consumption is rampant in its surrounding places An attempt to assess the histological trends in this area is madeMethodology Total of 450 lung cancer patients were studied in a span of 7 yearsResults Out of 450360 cases were histopathologically proven 255 7083 were males and 95 2638 were females with a male to female ratio of 271 Adeno carcinoma was found in 215 5972 being most common followed by squamous cell carcinoma 812250 small cell 23 638 large cell 12 33 and others 3175 Adenocarcinoma is the most common histopathological type seen in both males and females with 147 5764 cases and 63 6631 cases respectively Adenocarcinoma is the most common histopathological type seen in both smokers and nonsmokers with 246 6833 and 114 3166 respectivelyConclusions Adenocarcinoma is evolving to be the most common histological type in both smokers and nonsmokers in India Tobacco cessation and change to filtered cigarettes has globally reduced tobacco related histological types of lung cancers The aetiology of adenocarcinoma should be further evaluated in order to achieve an overall preventionnbsp Keywords Adenocarcinoma Lung cancer Squamous cell carcinoma
Authors and Affiliations
K. Kalyani, Pragati Rao, K. Chiranjeevi
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