CHARACTERISTIC OF THE BIOFILMFORMATION AND ADHESION PROPERTIES OF THE CLINICAL ISOLATES OF THE GENUS CANDIDA FUNGI
Journal Title: Наукові доповіді НУБіП України - Year 2017, Vol 2, Issue 2
Abstract
Wide use of invasive technologies in medicine creates new ecological niches for microorganisms and leads to the colonization, and then to the infection of patients with hospital strains. The article is devoted to the actual problem of adhesion and biofilms formed by fungi of the genus Candida in patients who have been hospitalized for a long time in the intensive care units of the multi-field hospital. The adhesive and biofilm-forming activity in 33 strains of fungi of the genus Candida isolated from different clinical materials was studied. Study of the adhesive properties and ability to form biofilm can be quite a trustworthy and convenient tool for evaluating the pathogenic potential of strains and prediction of the development of fungal infection. The investigated strains of fungi isolated from the same type of biological material, characterized by the ability to adhesion and biofilm formation, so this characteristic is statusbaritem. High-adhesive and average-adhesive strains were isolated from urine and from blood. The highest ability to form biofilms possessed the strains isolated from the urine. It has been established that strains with a high degree of adhesiveness formed biofilms more intensively than strains with medium and low adhesiveness
Authors and Affiliations
J. V. Sobkova, O. V. Pokas, G. V. Filonenko
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