Characterization and Management of Epithelioid Hemangioma on the Lip Mucosa: A Case Report

Journal Title: Journal of Dermatology Research - Year 2024, Vol 5, Issue 3

Abstract

Epithelioid Hemangioma (EH) is a rare benign vascular tumor characterized by well-formed blood vessels and epithelioid endothelial cells. Known as Angiolymphoid Hyperplasia with Eosinophilia (ALHE), the World Health Organization does not recommend the use of this term since 2020. Despite its common occurrence in subcutaneous soft tissues of head and neck, cases involving oral mucosa and other extra cutaneous areas are infrequent. This article presents a case of EH in an unusual location and discusses the differential diagnosis with other entities, including Kimura´s Disease (KD). We report the clinical case of a 26 year old man with no significant medical history who presented with a painless increase in volume on the right upper lip, subsequently diagnosed as EH through biopsy and histopathology. The lesion exhibited typical clinical features and a complex histological pattern including epithelioid endothelial cells and an inflammatory infiltrate rich in eosinophils. Diagnosis of EH is challenging due to morphological variability and the need to differentiate it from similar conditions such as KD. Differential diagnosis is crucial, especially in atypical locations. This case shows the importance of histopathology and complementary examinations in diagnosis and the need to consider KD in the differential diagnosis due to its therapeutic and prognostic implications. Therefore, it is concluded that EH, although benign, requires a rigorous diagnostic approach to differentiate it from similar diseases and manage it appropriately. Continuous control is essential due to the potential for recurrence. This case shows the importance of careful differential diagnosis, especially in atypical locations, to optimize management and improve patient outcomes.

Authors and Affiliations

Javiera Guíñez1, Diego Lazo-Pérez2, Rojas-Alcayaga Gonzalo1,3, Iván Gallegos3, Andrea Maturana-Ramírez1,2*

Keywords

Related Articles

Impacts of the COVID-19 Pandemic to the Skin and to Professionals Caring for the Skin

This is a brief review on the impact of Coronavirus disease 2019 (COVID-19) pandemic on the skin and the practice of dermatology. There are many skin manifestations of COVID-19. The most characteristic one would be mu...

Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study

Background: Effective treatments for pediatric periorificial dermatitis are limited. We assessed the clinical utility of oral Clarithromycin (CLR) in pediatric patients with periorificial dermatitis. Methods and Findi...

JAK Inhibitor Baricitinib in the Treatment of Oral Lichen Planus: A Case Report

Baricitinib, a JAK1/2 inhibitor, has been expanding its role as a therapeutic agent with recent FDA approval for dermatologic use with alopecia areata. Clinical trials are underway for further use of baricitinib for seve...

Flattened Nose Revealing Syphilitic Aortitis

Flattened nose also called syphilis nose is a deformation of the nose due to the destruction of the cartilage of the nasal septum: the lower segment of the nose collapses, undergoes recoil and retract, becoming embedded...

Vulvar Lesion Mimicking Vitiligo Revealing a Squamous Cell Carcinoma

Melanocytes respond to trauma or cutaneous inflammation by producing varying amounts of melanin, which manifests as either hyperpigmentation or hypopigmentation. Post inflammatory Hypopigmentation (PIH) is an acquired pa...

Download PDF file
  • EP ID EP745169
  • DOI https://doi.org/10.46889/JDR.2024.5303
  • Views 26
  • Downloads 0

How To Cite

Javiera Guíñez1, Diego Lazo-Pérez2, Rojas-Alcayaga Gonzalo1, 3, Iván Gallegos3, Andrea Maturana-Ramírez1, 2* (2024). Characterization and Management of Epithelioid Hemangioma on the Lip Mucosa: A Case Report. Journal of Dermatology Research, 5(3), -. https://europub.co.uk/articles/-A-745169