Chemical analysis, antioxidant and antimicrobial activities of leaves essential oil of Annona senegalensis pers. from Burkina Faso
Journal Title: World Journal of Pharmaceutical Sciences - Year 2018, Vol 6, Issue 1
Abstract
The aim of this study was to determine the chemical composition, antioxidant and antimicrobial properties of leaves essential oil of Annona senegalensis from Burkina Faso. Essential oil was obtained by hydrodistillation and analyzed by GC and GC/MS. Antioxidant activity of the essential oil was evaluated by DPPH radical scavenging assay and FRAP test and antimicrobial activity by disk diffusion method and microdilution method. Caryophyllene oxide (32.565%), humulen-1, 2-epoxide (5.85%), spathulenol (3.62%), linalool (2.525%), β- caryophyllene (2.446%) and δ-cadinene (2.012%) were the major compounds of A. senegalensis essential oil. The oil showed good radical scavenging power and moderate reducing power compared with quercetin, ascorbic acid and BHT. Essential oil of A. sengalensis exhibited high to weak antibacterial activity with inhibition diameters ranging from 08±00mm to 15.5±0.71mm and MIC value of 4% to 8%; MBCs were higher than the highest concentration tested. The oil inhibited all fungal strains with inhibition diameters between 10.5±0.71mm and 13.5±0.71mm, MIC value of 0.125% and 4% with MFC of 1% and 8%. Plants with radical antioxidant capacity are useful for medicinal applications and as food additive. Hence the essential oil of Annona senegalensis leaves could be a potential antioxidant and antimicrobial agent.
Authors and Affiliations
SEMDE Zénabou
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