Chemical composition of volatile extract of Gnaphaliumluteo-album l. Its and its antibacterial activity
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2015, Vol 3, Issue 7
Abstract
The quantitative and qualitative analysis of the oil by GC and GC-MS, led to the identification of 14 constituents, constituting 96.13 % of the volatile extract.It was mainly characterized by the dominant presence of hydrocarbons (41.6 %) followed by oxygenated sesquiterpene (25.1 %). Dodecane (31.10 %) was found as major compound with other major constituents6,10,14-trimethyl-2-pentadecanone (18.23 %), indol (8.12 %), 5-methyl undecane (7.99 %), γ-cuprene (7.03 %) and isoledene (6.05 %). The antimicrobial activity of the volatile extract was determined by well diffusion method. The extract was found to be significantly active for Klebsiellapneumoniae, Salmonella entericaandEscherichia coli and can be used as antimicrobial agent for these strains. High antibacterial activity of the oil against all microorganismsindicates good bioactive potential of the oil.
Authors and Affiliations
PoonamKushwaha| Department of Chemistry, DSB Campus, Kumaun University, Nainital, India., Darshan Singh| Department of Chemistry, DSB Campus, Kumaun University, Nainital, India., Ganga Bisht| Department of Chemistry, DSB Campus, Kumaun University, Nainital, India.
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