CLINICAL BENEFITS OF MILK THISTLE (SILYBUM MARIANUM): A RECENT REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 1
Abstract
Milk thistle (Silybum marianum) has been used for 2,000 years as an herbal remedy for a variety of ailments, particularly liver, kidney, and gall bladder problems. Milk thistle is widely used in Europe for hepatic and biliary disorders, and is beginning to be used to protect against nephrotoxicity as well. It protects the liver from several hepatotoxins, including Amanita mushrooms, acetaminophen and alcohol. Its primary active ingredient is silymarin, which has antioxidant and anti-inflammatory properties, and it may help the liver repair itself by growing new cells. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) protect the liver from toxins, including certain drugs such as acetaminophen (Tylenol), which can cause liver damage in high doses. Its leaves, flowers and roots have historically been considered a vegetable in European diets, and its fruits (achenes), which resemble seeds, have been roasted for use as a coffee substitute. The leaves of the plant are eaten in fresh salads and as spinach substitute, the stalks eaten like asparagus, and the flower heads served as one would an artichoke.
Authors and Affiliations
Patel Chirag J*| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Prof. Satyanand Tyagi| President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074., Umesh Kumar| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Patel Shreya| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Patel Pinkesh| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Chaudhari Bharat| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
Keywords
Related Articles
- EP ID EP1341
- DOI -
- Views 762
- Downloads 51
Cooking oil rancidification during deep frying causes health hazards
Many factors can affect the tendency of oil to become rancid. The first is too much exposure to air. Since oxidative rancidity is the most likely kind of rancidity to affect food oils, always want to keep those oils in b...
Formulation & evaluation of Ofloxacin sustained release matrix tablet
The present study aimed to formulate and evaluate sustained release matrix tablets of Ofloxacin to achieve sustained drug release. Sustained release matrix tablets of Ofloxacin were prepared by wet granulation method usi...
A study on clinical profile of abrus precatorius poisoning in R.M.M.C.H
Self harm has often been thought of as a problem particular to the industrialized worldIt is clear from many studies that not all people who die following acts of self-harm actually wish to die. Instead, the acts are use...
FLOATING DRUG DELIVERY SYSTEM: A REVIEW
Floating drug delivery systems (FDDS) was to organize the recent journalism with unique focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiolog...
FORMULATION AND OPTIMIZATION OF ONDANSETRON HYDROCHLORIDE ORODISPERSIBLE TABLETS
The demand for mouth dissolving tablets has been growing, during the last decade especially for geriatric and pediatric patients because of swallowing difficulties. Orodispersible tablets of Ondansetron hydrochloride wer...