COMPARITIVE STUDY OF MEMORY ENHANCING PROPERTY OF “MODAFINIL AND CISSAMPELOS PARIERA” IN MICE
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 5
Abstract
Piracetam is established learning and memory enhancing agent which have gained entry into the market.Modafinil, a novel wake-promoting agent and Cissampelos pariera , have been reported to have a similar clinical profile. The present study was undertaken to investigate the comparative effect of Modafinil , Piracetam and Cissampelos pariera on learning and memory in mice. Elevated plus maze and passive avoidance paradigm were employed to test learning and memory. Common doses of (200mg/kg.) Piracetam1 Cissampelos pariera and Modafinil were administered for 7 successive days in separate group of animals.
Authors and Affiliations
Prateek Bisht*| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Rekha. S| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Chandrashekhara. S| Dept. of Pharmaceutics, M.M College of Pharmacy, Belgaum, Karnataka, India-590016., Vineeth Chandy| Dept. of Pharmaceutical chemistry, T. John College of Pharmacy, Bangalore, Karnataka, India-560042., Prof. Satyanand Tyagi| President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), New Delhi, India-110074.
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