A review on pathophysiology and treatment of aplastic anaemia
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 7
Abstract
Aplastic anaemia is a medical condition in which the bone marrow is fails to make enough blood cells such as RBC, WBC & Platelets. It is mostly 2 types such as acquired and inherited and it is caused by exposure to chemicals (benzene and some carbmates), radiation (U.V), Drugs (Choramphenicol, carbamezepines etc), infection (virus) and immune disease. In aplastic anaemia diagnosis can be confirmed by bone marrow examination and it can be treated by immunosuppressive therapy, marrow stimulating agents and if aplastic anaemia is severe so used bone marrow transplantation.
Authors and Affiliations
Jyoti Nayak*| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India, Akanksha Singh| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India, Sant Lal| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India, Chetan K. Dubey| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India, Pushpendra K. Tripathi| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India, Shalini Tripathi| Department of Pharmacology, Rameshwaram Institute of Technology & Management, Lucknow, U.P., India
FORMULATION DEVELOPMENT AND CHARACTERIZATION OF FAST DISSOLVING ACETAMINOPHEN TABLETS
The aim of the present work is to formulate a tablet which disintegrate and dissolve rapidly and give its rapid onset of action. Acetaminophen is an analgesic, antipyretic drug having bitter taste. In present study an at...
IMPORTANCE OF GARLIC (ALLIUM SATIVUM): AN EXHAUSTIVE REVIEW
Allium sativum, also known as Clove Garlic is part of the Lilliceae plant family. Garlic is a member of the onion family and is one of nature's most versatile medicinal plant. The name “Allium sativum” is derived from th...
INDUSTRIAL PROCESS VALIDATION: A REVIEW
Validation is defined in the supplementary information section of the Federal Register as “a QA function that helps ensure drug product quality by providing documented evidence that the manufacturing process consistentl...
ETHOSOMES: A NOVEL APPROACH IN TRANSDERMAL DELIVERY OF THE DRUGS
Skin acts as a major target as well as a principal barrier for topical/transdermal drug delivery. Despite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the stratum corne...
A RECENT APPROACH FOR SOLUBILITY AND BIOAVAILABILITY ENHANCEMENT: SOLID DISPERSION
Currently only about 8% of the new molecules have both high solubility and permeability. The drugs therapeutic efficacy depends upon the bioavailability and ultimately upon the solubility. Improving oral bioavailability...