Chest Computed Tomography and Severity Markers in COVID-19
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2021, Vol 1, Issue 05
Abstract
Background: Computed Tomography chest scan is a tool for classification of COVID 19 disease. We propose there is a relation between computed tomography severity index and inflammation biomarkers. Methods: We performed a retrospective analysis of hospitalized COVID 19 patients in Mexicali´s General Hospital, during the period of March 2020 to December 2020. The inclusion criteria was over 18 years old, confirmatory RT- PCR nasal swab and available CT chest scan. We extracted data of medical records; variables studied were age, sex, date of symptom onset, date of admission, chest computed tomography score, RT-PCR result, laboratory values (D-dimer, fibrinogen, ferritin, procalcitonin, C- reactive protein, total leukocytes, lymphocytes), and outcome. Results: From March 2020 to December 2020, 397 patients were recruited that fulfilled the inclusion criteria from a 700 patient database. Statistically significant differences after t tests between survivors and non-survivors were found for C-reactive protein (means 47.1 ± 36 vs. 80.1 ± 54 ; p = 0.0009), procalcitonin (means 961 ± 279 vs. 1,032 ± 283; p = 0.023), white blood cells (means 10.57 ± 4.46 vs. 12.33 ± 6.22; p = 0.0026) and lymphocytes (means 0.79 ± 0.50 vs. 0.68 ± 0.40; p value= 0.026). Conclusions: Laboratory and imaging studies are fundamental for stratification andoutcome pre diction in COVID-19 patients. With these findings we can determine the prognosis of a patient, have a better approach, and search specifically for the relevant severity markers such as fibrinogen, white blood cells, lymphocytes, and C-reactive protein in hospitals with limited resources.
Authors and Affiliations
Gisel Viviana Licón Martínez MD, Aranza Elena García Aréstegui, MD, Marina Estrada-Rodriguez, Katya Lorena Wilhelmy-Ledesma, Joaquin Córdova Erberk, Gabriel Rocha-González, MD, Fernando Augusto Domínguez-García, MD, Miguel Angel Gaxiola-García, MD, MSc, Hiram Javier Jaramillo-Ramírez, MD
Keywords
Related Articles
- EP ID EP713223
- DOI 10.47191/ijmscrs/v1-i5-01
- Views 101
- Downloads 0
Electrocardiographic Changes in Young Healthy Male Smokers
Background: Smoking increasesthe risk of CVD, however, the magnitude of this increase in riskvariessubstantivelyaccordingtoarangeoffactors.Smoking-relatedCVDrisksarehighestin current and recent smokers, compa...
Identifying Risk Factors for Complicated Duodenal Ulcer in Children
In recent years, there has been an increase in the incidence of duodenal ulcer and an increase in the number of complicated forms. Bleeding from duodenal ulcers is the most formidable complication and occupies one of the...
Hypoglossal Canal and Condylar Canal Variations: A Case Report
The hypoglossal canal is a permanent element of the human skull (Wysocki et al. 2004). The hypoglossal canal is situated occipital bone (Sakamoto2019). Variations can be found in this canal. S...
Peritoneal Tumors of Mullerian Origin: A Case Report and Review of the Literature
Primary peritoneal tumors share a common anatomical site and therefore their clinical manifestations are very similar. When peritoneal masses are detected, the tentative initial diagnosis is secondary to metastatic dise...
Segmental Optic Atrophy with Adrenoleukodystrophy ABCD1 Gene Variant
We report a case of Adrenoleukodystrophy ABCD1 gene variant presenting with segmental optic atrophy in a 34-year-old male.The patient presented to our Neuro-Ophthalmology clinic with complaints of defective vi...