Chest Computed Tomography and Severity Markers in COVID-19
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2021, Vol 1, Issue 05
Abstract
Background: Computed Tomography chest scan is a tool for classification of COVID 19 disease. We propose there is a relation between computed tomography severity index and inflammation biomarkers. Methods: We performed a retrospective analysis of hospitalized COVID 19 patients in Mexicali´s General Hospital, during the period of March 2020 to December 2020. The inclusion criteria was over 18 years old, confirmatory RT- PCR nasal swab and available CT chest scan. We extracted data of medical records; variables studied were age, sex, date of symptom onset, date of admission, chest computed tomography score, RT-PCR result, laboratory values (D-dimer, fibrinogen, ferritin, procalcitonin, C- reactive protein, total leukocytes, lymphocytes), and outcome. Results: From March 2020 to December 2020, 397 patients were recruited that fulfilled the inclusion criteria from a 700 patient database. Statistically significant differences after t tests between survivors and non-survivors were found for C-reactive protein (means 47.1 ± 36 vs. 80.1 ± 54 ; p = 0.0009), procalcitonin (means 961 ± 279 vs. 1,032 ± 283; p = 0.023), white blood cells (means 10.57 ± 4.46 vs. 12.33 ± 6.22; p = 0.0026) and lymphocytes (means 0.79 ± 0.50 vs. 0.68 ± 0.40; p value= 0.026). Conclusions: Laboratory and imaging studies are fundamental for stratification andoutcome pre diction in COVID-19 patients. With these findings we can determine the prognosis of a patient, have a better approach, and search specifically for the relevant severity markers such as fibrinogen, white blood cells, lymphocytes, and C-reactive protein in hospitals with limited resources.
Authors and Affiliations
Gisel Viviana Licón Martínez MD, Aranza Elena García Aréstegui, MD, Marina Estrada-Rodriguez, Katya Lorena Wilhelmy-Ledesma, Joaquin Córdova Erberk, Gabriel Rocha-González, MD, Fernando Augusto Domínguez-García, MD, Miguel Angel Gaxiola-García, MD, MSc, Hiram Javier Jaramillo-Ramírez, MD
Keywords
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- EP ID EP713223
- DOI 10.47191/ijmscrs/v1-i5-01
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