Rola witaminy D w zachowaniu zdrowia i zdolnościach wysiłkowych sportowca

Autophagy in brain ischemia

Autophagy is an intracellular process of macromolecule and organelle degradation, which plays an important role both in maintaining homeostasis and in responding to various harmful stimuli. Recent studies clearly indicat...

Rola hepcydyny w metabolizmie żelaza w przebiegu nieswoistych zapaleń jelit

Hepcydyna to 25-aminokwasowy peptyd syntetyzowany głównie w hepatocytach, który odgrywa zasadniczą rolę w regulacji ogólnoustrojowej gospodarki żelazem. W odpowiedzi na stan zapalny, hepcydyna działa przez degradację fer...

TSG-6 protein and its role during maturation of ovarian follicles

TSG-6 is an ~35 kDa glycoprotein belonging to the hyaluronan binding family. Its expression is induced as a result of an inflammatory condition and during ovulation. TSG-6 is a crucial protein engaged in extracellular m...

Transmembrane transporters ABCC – structure, function and role in multidrug resistance of cancer cells

Resistance to cytotoxic drugs is a significant problem of systemic treatment of cancers. Apart from drug inactivation, changes in target enzymes and proteins, increased DNA repair and suppression of apoptosis, an importa...