CHITOSAN HYDROGELS FOR DRUG DELIVERY AND TISSUE ENGINEERING APPLICATIONS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 12
Abstract
Chitosan has been extensively used to prepare hydrogel systems. The fact that chemically and ionically crosslinked chitosan hydrogels can slowly release drugs through swelling have enabled their use in drug delivery applications. In addition, the high porosity of these hydrogels ensures a more effective cell loading and depending on the pore size and interconnectivity, it can lead to cell differentiation and eventually tissue formation. The purpose of this review is to take a closer look at the use of chitosan hydrogels to prepare drug delivery systems and scaffolds for tissue engineering. Aspects involving chitosan structure, physicochemical properties and biological applications are also discussed. In addition, this article reviews the methods used to prepare chitosan hydrogels and the mechanisms involved in the release of drugs.Â
Authors and Affiliations
Eduardo Pereira De Azevedo
Keywords
Related Articles
- EP ID EP578025
- DOI -
- Views 70
- Downloads 0
ANALYTICAL METHOD DEVELOPMENT & VALIDATION OF ARTEMETHER IN BULK DRUG BY RP- HPLC METHOD AS PER ICH GUIDELINES
Objective: An accurate, precise, rapid & economical RP-HPLC method was developed for the estimation of Artemether as per International Conference on Harmonization (ICH) guideline in pharmaceutical dosage form using u...
A COMPARATIVE PHARMACOGNOSTICAL EVALUATION OF THREE BOTANICAL SOURCE PLANTS OF JIVANTI
Objective: This study was undertaken to carry out a comparative pharmacognostical evaluation of three botanical source plants used in the name of classical Ayurvedic drug Jivanti.Methods: Leaves of three source plants of...
PHYSIOCHEMICAL INVESTIGATION AND BIOVALUATION OF TiO2 NANOCRYSTALS SYNTHESIZED BY CHEMICAL AND GREEN ROUTE
Objectives: In this present work, we have compared titanium dioxide nanocrystals synthesized by both chemical method and biological method from Titanium tetra isopropoxide as precursor. The biological method was performe...
LOADING OF CLARITHROMYCIN AND PACLITAXEL ON SYNTHESIZED CdS/NiO NANOPARTICLES AS PROMISING NANOCARRIERS
Objective: In this study cadmium sulfide (CdS) and nickel oxide (NiO) nanoparticles were synthesized and applied as novel nanocarriers for antibacterial drug clarithromycin (CLA) and anticancer drug paclitaxel (PTX) to i...
DETERMINATION OF ALPRAZOLAM AND FLUOXETINE HCl FROM SPIKED RAT PLASMA USING HPTLC WITH UV DETECTION
Objective: The main aim of this study was to develop a rapid, simple and selective validated high-performance thin-layer chromatographic (HPTLC) method with UV detection for the estimation of alprazolam and fluoxetine HC...