Chlorpyrifos chronic toxicity in broilers and effect of vitamin C
Journal Title: Open Veterinary Journal - Year 2011, Vol 1, Issue 2
Abstract
An experiment was conducted to study chlorpyrifos chronic toxicity in broilers and the protective effect of vitamin C. Oral administration of 0.8 mg/kg body weight (bw) (1/50 LD50) chlorpyrifos (Radar®), produced mild diarrhea and gross lesions comprised of paleness, flaccid consistency and slightly enlargement of liver. Histopathologically, chlorpyrifos produced degenerative changes in various organs. Oral administration of 100 mg/kg bw vitamin C partially ameliorated the degenerative changes in kidney and heart. There was insignificant alteration in biochemical and haematological profiles. It is concluded that supplementation of vitamin C reduced the severity of lesions induced by chronic chlorpyrifos toxicity in broilers.
Authors and Affiliations
A. M. Kammon| Department of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Al-Fateh University, Tripoli, Libya, R. S. Brar| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, S. Sodhi| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, H. S. Banga| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, J. Singh| Department of Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Canada, N. S. Nagra| Department of Livestock Production and Management, College of Veterinary Science, GADVASU, Ludhiana, India
Keywords
Related Articles
- EP ID EP9245
- DOI -
- Views 727
- Downloads 45
Review on mechanisms of dairy summer infertility and implications for hormonal intervention
In dairy cows and buffaloes, summer heat stress (HS) reduces milk yield and delays return to pregnancy leading to financial loss. Clues for effective interventions against summer infertility (SI) lie in understanding th...
Post-surgical treatment of thyroid carcinoma in dogs with retinoic acid 9 cis improves patient outcome
The objective of the present study was to compare the effects of isotretinoin 9-cis (RA9-cis) as a post-surgery treatment of thyroid carcinoma to a traditional treatment (doxorubicin) and no treatment. Owners who did no...
Environmentally toxicant exposures induced intragenerational transmission of liver abnormalities in mice
Environmental toxicants such as chemicals, heavy metals, and pesticides have been shown to promote transgenerational inheritance of abnormal phenotypes and/or diseases to multiple subsequent generations following paren...
Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (Gallus Domesticus): morphological heterogeneity of pluripotential germ cell during tumorigenesis
Spontaneous ovarian teratoma was found in a seven-week-old female Chunky broiler chicken that was slaughtered for food. On post-mortem inspection, a spherical tumor mass attaching to a juvenile ovary was found in the ab...
Non-invasive assessment of equine muscular function: A case study
Assessment of muscle function after an injury or during recovery is of great importance in the veterinary field. Accelerometry, bioimpedance analysis and mechanomyography/acoustic myography have been used to assess hum...