Chlorpyrifos chronic toxicity in broilers and effect of vitamin C

Journal Title: Open Veterinary Journal - Year 2011, Vol 1, Issue 2

Abstract

An experiment was conducted to study chlorpyrifos chronic toxicity in broilers and the protective effect of vitamin C. Oral administration of 0.8 mg/kg body weight (bw) (1/50 LD50) chlorpyrifos (Radar®), produced mild diarrhea and gross lesions comprised of paleness, flaccid consistency and slightly enlargement of liver. Histopathologically, chlorpyrifos produced degenerative changes in various organs. Oral administration of 100 mg/kg bw vitamin C partially ameliorated the degenerative changes in kidney and heart. There was insignificant alteration in biochemical and haematological profiles. It is concluded that supplementation of vitamin C reduced the severity of lesions induced by chronic chlorpyrifos toxicity in broilers.

Authors and Affiliations

A. M. Kammon| Department of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Al-Fateh University, Tripoli, Libya, R. S. Brar| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, S. Sodhi| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, H. S. Banga| Department of Veterinary Pathology, College of Veterinary Science, GADVASU, Ludhiana, India, J. Singh| Department of Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Canada, N. S. Nagra| Department of Livestock Production and Management, College of Veterinary Science, GADVASU, Ludhiana, India

Keywords

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  • EP ID EP9245
  • DOI -
  • Views 445
  • Downloads 45

How To Cite

A. M. Kammon, R. S. Brar, S. Sodhi, H. S. Banga, J. Singh, N. S. Nagra (2011). Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Veterinary Journal, 1(2), 21-27. https://europub.co.uk/articles/-A-9245