Chordoid Glioma of The Third Ventricle: A Case Report and Review of Literature
Journal Title: Journal of Neurological Sciences-Turkish - Year 2012, Vol 29, Issue 1
Abstract
Chordoid glioma of the third ventricle is a newly described tumor. In the present study, we report a case of chordoid glioma and review various, previously published case series and individual case reports of chordoid glioma. With regard to the case report, the patient was a 53-year-old woman whose primary symptoms included decreased vision, a visual field deficit on the nasal side, and headache. CT and MRI demonstrated a tumor that was located in the supra-sellar region of the sella turcica. Microscopically, the tumor was composed of epithelioid cells in a mucinous background with abundant eosinophilic cytoplasm arranged in nests and strands. A mixed, chronic inflammatory infiltrate composed of lymphocytes and plasma cells was abundant in the peripheral portion of the tumor. Immunohistochemically, the tumor cells expressed GFAP and vimentin, whereas EMA was found to only label individual cells. Less than 1% of the cells were Ki-67 positive. The results demonstrate that chordoid gliomas of the third ventricle can be differentiated from other tumors based on clinical and histopathological features as well as immunohistochemical staining.
Authors and Affiliations
Gui XIAN, Zhao YAODONG, Lou MEIQING
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