Chromatin Remodeling Complexes: The Regulators of Genome Function

Journal Title: Global Journal of Zoology - Year 2016, Vol 1, Issue 1

Abstract

Genome in eukaryotes is large enough to be accommodated in tiny nucleus. It is required to achieve high degree of compaction for getting into the nucleus. Compaction is achieved by folding the DNA in the form of chromatin. But chromatin acts as general repressor for the entire genomic functions. Therefore, it requires being selectively unpacked for gene expression. However this packing and unpacking of chromatin need to temporally and spatially regulated for differential regulation of genomic functions like DNA replication, repair, recombination and transcription. Chromatin remodeling factors regulate structure and function of chromatin in time and space to facilitate various genomic functions. Chromatin remodeling complexes can be broadly categorized into those that carry out remodeling by utilizing energy from ATP hydrolysis and those that covalently modify chromatin proteins and thus bring about permanent yet reversible alteration in the chromatin structure.

Authors and Affiliations

Pandey Shashibhal M

Keywords

Related Articles

Assessment of Chromium Oxide Nanoparticles Intake in Rattus norvegicus by Primary Renal Function Markers and RBC Architecture

Haematological tests are signifi cant diagnostic tools that are equally valuable as indicators of toxic insult or stress due to xenobiotics and environmental fl uctuations. Present study was designed to investigate alter...

Promising role of Carob (Ceratonia siliqua L) phytochemical components against neurotoxicity induced by monosodium glutamate

The phytochemical constituents of Carob (Ceratonia siliqua L) showed therapeutic medical importance especially concerning neurotoxicity which represents the major public health problem. Neurodegenerative disorders are de...

Diversity and Distribution of Ants (Hymenoptera: Formicidae) Nests in the Anjac Campus, Sivakasi, Tamil Nadu

The present communication deals with diversity and nesting habitat of ants in ANJAC, Campus, Sivakasi. In the present investigation, we identified ten species belonging to three subfamilies inside the campus. Richness an...

Babesia Microti – Known and Unknown Protists

B. microti is known as the main etiological agent of human babesiosis and there are some case studies for that disease, highlighting the fact that this is an important “emerging tick-borne disease”. However a lot of info...

Prenatal Stress Reduces Learning and Memory in Pre-pubertal, Young, and Adult Rats of Both Sexes

Prenatal stress (PS) induced by immobilization produces defi ciencies in spatial learning and information retrieval. These defi ciencies seem to be larger in males than in females, and have been explained as an effect of...

Download PDF file
  • EP ID EP556940
  • DOI 10.17352/gjz.000003
  • Views 55
  • Downloads 0

How To Cite

Pandey Shashibhal M (2016). Chromatin Remodeling Complexes: The Regulators of Genome Function. Global Journal of Zoology, 1(1), 7-13. https://europub.co.uk/articles/-A-556940