Chromogenic Spectrophotometric Estimation Of Deflazacort In Bulk & Its Formulation Using 2, 2 Bi Pyridyl Reagent
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 4
Abstract
Simple, precise, economic, less time consuming visible spectroscopic method for Deflazacort was developed by using 2, 2- Bipyridyl and Ferric Chloride. The absorption maximum of the chromogen was found to be 540 nm. The developed method was obeying Beer Lambert’s law in the range of 50-250 µg/ml concentration. The method has also been statistically evaluated and the results were within the regulated limits. Molar absorptivity, Sand ell’s sensitivity and correlation–co-efficient were found to be 1.406 x 103 , 0.143 and 0.999 respectively and the method is free from the interferences of other additives present in the tablet formulation.
Authors and Affiliations
Hafsa Sarwath, Hanaa Fatima Moin, Sumaiya Tamkeen, Anupama Koneru,, Imam Pasha . S
Keywords
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