Chronic Obstructive Pulmonary Disease (COPD)
Journal Title: Journal of the Indian Medical Association - Year 2019, Vol 117, Issue 7
Abstract
Chronic obstructive pulmonary disease (COPD) is a common disease with high global morbidity and mortality. COPD involves accelerated ageing of the lungs and an abnormal repair mechanism that might be driven by oxidative stress. Acute exacerbations, which are mainly triggered by viral or bacterial infections, are important as they are linked to a poor prognosis. The mainstay of the management of stable disease is the use of inhaled long-acting bronchodilators, whereas corticosteroids are beneficial primarily in patients who have coexisting features of asthma, such as eosinophilic inflammation and more reversibility of airway obstruction. Apart from smoking cessation, no treatments reduce disease progression.
Authors and Affiliations
Surya Kant, Jyoti Bajpai, Akshyaya Pradhan
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