Chronic Pain after Laparoscopic Inguinal Hernia Repair Depends on Mesh Implant Features: A Clinical Randomised Trial
Journal Title: Open Journal of Pain Medicine - Year 2017, Vol 1, Issue 1
Abstract
Chronic pain is a severe complication of mesh-based inguinal hernia repair. In this prospective, clinical, randomized, double-blind study we investigated the biocompatibility of three different meshes and their influence on chronic pain. One hundred eighty male patients with primary inguinal hernia undergoing laparoscopic transabdominal polypropylene plastic (TAPP) were randomized for using a heavyweight (108 g/m2), double-filament polypropylene mesh (Prolene, 10X15 cm, group A, n = 60), a multifilament, heavyweight variant (116 g/m2) of polypropylene mesh (Serapren, 10X15 cm, group B, n = 60), or a composite mesh (polyglactin / polypropylene) (Vypro II, 10X15 cm, group C, n = 60). Groups were compared in terms of complications, pain development and life quality (SF-36 Health Survey). Convalescence in group A lasted more time than in groups B and C: mean-term values of the visual scales for pain development were significantly higher (p<0.05), incapacity for work was 8.2 days longer, and urological adverse effects were stronger. The mean-term development of life quality was significantly lower in group A up to the 12th week. There were no significant differences between groups B and C. Beyond the 12th postinterventional week the differences were not statistically significant. Independent of the mesh implanted there was still 5% of patients suffer chronic pain 60 months later.
Authors and Affiliations
Langenbach Mike Ralf, Berengolts Alexandre
Keywords
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- EP ID EP559470
- DOI 10.17352/ojpm.000004
- Views 33
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