Chronic Suppurative Otitis Media - Empiric Quinolones in Adults
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2014, Vol 9, Issue 2
Abstract
Objective: The aim of the study was to determine the most prevalent organisms in chronic otitis media in adults and their susceptibility to various antimicrobials so that an appropriate empiric antibiotic can be started promptly while awaiting the results of the culture and sensitivity. Design: Prospective observational study. Place and Duration of Study: NIMS hospital, from July 2011 to July 2012. Subject and Methods: A total of 156 patients more than 15 years of age who were having discharge from one or both ears for at least 1 week with tympanic membrane perforation were included in the study. A sample of the ear discharge was collected on the swab and cultured on appropriate media. Out of 156 patients, 96(61.5%) were males and 60(38.9%) were females. The organisms isolated were Staphylococcus aureus in 79(50.6%), Pseudomonas aeruginosa in 45 (28.8%) patients and Proteus mirabilis 17 (10.9%), Escherichia coli, Acinetobacter sp and streptococci 14(9.03%) patients. Staphylococcus aureus was the commonest organism isolated followed by Pseudomonas aeruginosa and Proteus mirabilis .54(34.6%) of Staphylococcus aureus were sensitive to gentamicin, 52(33.3%) to ciprofloxacin and 42 (26.9%) to both ciprofloxacin and gentarnicin. Among the Pseudomonas aeruginosa isolates 40 (25.6%) were sensitive to gentanicin, 27(17.3%) to ciprofloxacin and 22 (14.1%) to both ciprofloxacin and gentarnicin. Out of 155 patients 93(60%) had isolates which were sensitive to ciprofloxacin and 62(40%) were resistant to it, 114 patients (73.1%) had isolates which were sensitive to gentamicin whereas 33(27%) were resistant. Similarly 35 isolates (22.4%) were sensitive to sulphamethoxazole/ trimethoprim whereas 66(42.3%) were resistant. Among Proteus mirabilis isolates 12 were sensitive to gentamicin, 11 were sensitive to ciprofloxacin and 11 were sensitive to both ciprofloxacin and gentamicin. Conclusion: Ciprofloxacin can be recommended to be given empirically in adults with chronic discharging ears.
Authors and Affiliations
Gurleen Kaur
Keywords
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