CIGARETTE SMOKING IS THE LOWER RISK OF PARKINSON DISEASE
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2018, Vol 4, Issue 9
Abstract
Parkinson disease is the one of the most common neurologic disorder, affecting approximately 1% of individuals over than 60 years causing progressive disability that can be slowed, but not halted, by treatment. As a major component of tobacco smoke, nicotine has been proposed to be asubstance for preventing against Parkinson disease risk. With a key role in regulating straital activity and behaviours mediated through the dopiminergic system. Animal studies also showed that nicotine could modulate dopamine transmission and reduce levadopaenduced dysakinesias. However, previous clinical trials yield contaversial results regarding nicotine treatment. In this review, we updated epidemiological, preclinical and clinical data, and studies on nicotine from diet.
Authors and Affiliations
Suresh Undati
Keywords
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