Clinical and Biological Analysis of 149 Patients under Arv Tri-Therapy Treatment (Zidovudine-Lamivudine-Nevirapine) at National Centre of Blood Donors of Abidjan in Côte D’ivoire
Journal Title: Journal of Physiology and Pharmacology Advances - Year 2014, Vol 4, Issue 6
Abstract
In order to assess the effects of antiretroviral drugs on the local population, a descriptive study was conducted on the tri-therapy ZIDOVUDINE-LAMIVUDINE-NEVIRAPINE. The 149 patients studied were selected from the patients infected with HIV, who started treatment at National Center of Blood Donors in Abidjan, Côte d'Ivoire. These patients received regular treatment for 36 months, blood samples were taken every 6 months, clinical and laboratory assessments were performed. The results showed that all patients were infected with HIV-1 type. The analysis also showed a predominance of women and youths (17 to 35 years) in this studied population. Unmarried and employees in the private sector were the most infected, while the most important part of the patients were living in Yopougon, a district of Abidjan. Clinical and biological parameters analyzed showed positive impact of the treatment characterized by the increase of CD4+. The treatment did not show toxic effect on the liver and the kidney measured through the rate of creatinine and transaminases (TGO, TGP). The good level of Karnofsky score, the Body Mass Indice and the Brachial Perimeter reflected the good clinical status of patients.
Authors and Affiliations
W. M. O. Tovi, F. S. S. Ouattara , Y. Abo , A. Minga , K. Kouakou
Keywords
Related Articles
- EP ID EP88620
- DOI -
- Views 141
- Downloads 0
Effect of Exercise and Quercetin on Obesity Induced Metabolic and Renal Impairments in Albino Rats
Obesity has been described as a state of chronic oxidative stress and inflammatory reaction. This study was carried out to clarify the effect of exercise and antioxidant quercetin on oxidative stress and inflammatory rea...
Mechanisms Mediating the Protective Effect of Curcumin on Vascular Endothelial Dysfunction Induced by High Glucose
To investigate the antioxidant and vascular protective effect of curcumin, principle curcuminoid (a natural phenol) of the popular Indian spice and traditional medicine turmeric, on vascular endothelial dysfunction subse...
Effects of Extracts of Triplochiton Scleroxylon (K. Schum) on Plasma Glucose and Lipid Peroxidation in Normal and Streptozotocin—Induced Diabetic Rats
T. scleroxylon also known as ‘obeche’ and used in some of the rural areas in Nigeria in the treatment of diabetes mellitus was investigated in this study for lipid peroxidative activities. Plasma glucose and malondialdeh...
Effect of Extracorporeal Unfractionated Heparin on Hematological and Electrolyte Markers in Hemodialyzed Patients
End-Stage renal disease is the final stage of chronic kidney disease (CKD), which can be managed by hemodialysis (HD), peritoneal dialysis, or renal transplantation. This study was conducted to investigate the changes in...
Sympathetic Activity and Meditation-Gender Based Variability
The current study was done to see the gender variability in the sympathetic activity as a result of Rajyoga Meditation. For this study we selected 50 participants, 27 males and 23 females in age group 25 to 60 years, per...