CLINICAL AND DEMOGRAPHIC CHARACTERISTICS OF FAMILIAL MULTIPLE SCLEROSIS IN THE INNER AEGEAN REGION
Journal Title: Kocatepe Medical Journal - Year 2024, Vol 25, Issue 2
Abstract
OBJECTIVE: Multiple sclerosis (MS) is a common autoimmune demyelinating disease of the central nervous system (CNS). In this study, it was aimed to collect patients with MS retrospectively, to compare the characteristics of familial and sporadic MS patients in Turkish population, and to determine the frequency of familial MS patients and the clinical and demographic characteristics of these patients. MATERIAL AND METHODS: This cross-sectional record-based study was conducted between 01 January 2022 and 01 June 2022 in Afyonkarahisar Health Sciences University, Department of Neurology, with the data of patients with MS diagnosis and followed-up according to the 2017 McDonald criteria. Demographic data, clinical findings, age at onset, mean disease duration, onset symptoms and MS subtypes of the patients were evaluated. RESULTS: The frequency of familial MS (FMS) in the Turkish population was 7.3%. The presence of FMS was not found to be associated with early disease age. The most common initial symptom was sensory symptoms, and the most common MS subtype was relapsing remitting MS, and the Extended-state disability scale score was calculated, and no relation was found between the presence of FMS and high disease activity. CONCLUSIONS: The FMS rate in the Turkish population was found to be more similar to Euro-Latin countries. Clinical and demographic characteristics were found to be similar to those of Europe and the Middle East.
Authors and Affiliations
Gökçe ZEYTİN DEMİRAL, Selin BETAŞ AKIN
Keywords
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- EP ID EP740632
- DOI https://doi.org/10.18229/kocatepetip.1293262
- Views 25
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