FOLLOW-UP AND TREATMENT OF INFLAMMATORY BOWEL DISEASE: A RETROSPECTIVE STUDY
Journal Title: Kocatepe Medical Journal - Year 2021, Vol 1, Issue 22
Abstract
OBJECTIVE: The aim of this retrospective study was to investigate the socio-demographic and clinical characteristics as well as the diagnosis and treatment of patients with Inflammatory Bowel Disease between 1990 and 2009. MATERIAL AND METHODS: Between 1990 and 2009, the records of 237 patients diagnosed with Inflammatory Bowel Disease in the Gastroenterology Clinic of Faculty of Medicine were examined. The age, sex, smoking history, endoscopy and histopathology findings of the patients, local and systemic complications developed in the patients, types of treatment applied and reasons for surgical treatment were examined. RESULTS: Between 1990 and 2009, 144 Ulcerative Colit, 73 Crohn Disease and 20 Indeterminate Colit patients were followed. The mean age of diagnosis, at the time of diagnosis of Ulcerative Colit patients was 37 years. 28.7% patients had left colon involvement, 25.2% patients had pancolitis, and 21% patients had proctitis (p<0.01). Erythema nodosum in one patient, sacroiliitis in 3 patients, primary sclerosing cholangitis in 3 patients, and malign transformation in one patient were determined as systemic complications. The mean age was 35 years in patients with Crohn Disease. Involvement of colon and small intestine was determined in %34 and %64,2 patients, respectively. Uveitis in 4 patients, sacroiliitis in 5 patients were determined as systemic complications. 222 patients were treated with 5-ASA. Immunosuppressive treatment was given to 6 patients. 159 patients were given mono treatment (5-ASA) while 19 patients were given combine treatment. CONCLUSIONS: Understanding of the prognosis and clinical course are important for determining medical and surgical treatment and follow up strategies for different subgroups of the patient.
Authors and Affiliations
Hatice HAMARAT,Tuncer TEMEL
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