Clinical and epidemiological features of chronic pancreatitis course associated with atherosclerosis
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 3
Abstract
The article describes and analyzes dyslipidemic disorders, the degree of pancreatic external secretion insufficiency in patients with chronic pancreatitis. The purpose of our study is to study the changes in the blood lipid profile in patients with chronic pancreatitis depending on the degree of pancreatic external secretion insufficiency in residents of the city and villages. We carried out the 13C-mixed triglyceride respiratory test (13C-MTRT) and the 13C-amylase respiratory test (13C-ART) to detect the pancreatic external secretion insufficiency (PESI). Changes in the blood lipid profile were based on the violations in the lipidogram (determination of total blood cholesterol level (TC), triglycerides (TG), high density lipoproteins (HDL), and low density lipoproteins (LDL), atherogenicity coefficient (CA)). All examined patients with combination of chronic pancreatitis (CP) and athe¬rosclerosis have lipid metabolism disorders, but the changes in the city residents are more significant as compared with the rural population. It was also found that the most pronounced violation of the PESI was observed in patients with CP and lipid metabolism disorders, who were residents of the city. In these patients, during the 13C- MTRT, the maximum concentration of 13СО2 between 150 and 210 minutes were at the level of 4.9±0.7%; total concentration of 13СО2 at the end of the study (360 min.) – 17,1±0,3% and were statistically significant in comparison with the control group.
Authors and Affiliations
E. S. Sirchak, S. M. Opalenyk
Keywords
Related Articles
- EP ID EP436045
- DOI 10.26641/2307-0404.2018.3(part1).142373
- Views 88
- Downloads 0
Corresponding member of NAS of Ukraine L.V. Usenko is 80
Сучасні підходи до проведення поглиблених медичних оглядів військовослужбовців Служби Безпеки України
Исследованием установлено, что нормативная база по вопросам диспансеризации в системе СБ Украины не в полной мере регламентировала ее проведение, что потребовало разработки и обоснования новой организационной модели для...
Обгрунтування шляхів удосконалення анкетно-опитувального методу оцінки фактичного харчування населення
Обоснование путей совершенствования анкетно-опросного метода оценки фактического питания населения. Ельцова Л.Б., Омельчук С.Т. Состояние фактического питания населения Украины свидетельствует о значительной распростран...
Studying aerococci impact on colonization of intestinal mucous membrane with vibrions and ability to destroy staphilococus toxin
One of the promising methods of prevention and treatment of intestinal infections is the use of probiotics. A series of experiments was carried out to study the protective effect of A. viridans vibrio in experimental vib...
The role of thyroid hormones in regulating of fatty acid spectrum of brain lipids: ontogenetic aspect
In experiments on rats of three age groups the role of thyroid hormones in the regulation of fatty acid spectrum of cortical and hippocampus lipids was studied. It was found that on the background of decreased thyroid st...