Clinical and Neurological Changes in Children with Down Syndrome Based on The Cytogenetic Profile
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2021, Vol 1, Issue 07
Abstract
Down syndrome is the most common chromosomal pathology. It occurs when another chromosome appears in the 21st pair as a result of a random mutation. Often, children with Down syndrome (DS) and related disorders have some neurological problems, severe forms of stereotyped behavior. The purpose of this article was to study the neurological conditions of children with DS. Clinical, neurological, studies were performed in 120 children (75 boys, 45 girls) with DS. It was found that in children with trisomy, neurological deficits in the form of speech disorders, fine motor skills of the hand, disorders of the coordination sphere and autonomic dysregulation are more severe than in children with mosaic and translocation types.
Authors and Affiliations
Saodatkhon Mukhamadkhanovna Salikhova, Yakutkhon Nabiyevna Madjidova
Keywords
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- EP ID EP713301
- DOI 10.47191/ijmscrs/v1-i7-07
- Views 31
- Downloads 0
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