Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 2
Abstract
The purpose of this study was to determine the efficacy of using Wobenzim as a general therapy in the complex treatment of generalized periodontitis. 61 patients, I-II degree of severity, with tooth safety in an amount of at least 90%, without concomitant general pathology requiring treatment for the current time were examined. Comparative effectiveness of treatment was studied in 2 groups similar in all clinical indices. The main (31 people) patients, along with the symptomatic treatment received Wobenzim; control (30 people) - polytherapy (immunocorrecting, antioxidant, antimicrobial agents). As a result of the generally accepted clinical, paraclinical, immunological and biochemical studies conducted during the treatment and at long-term follow-up, it was found that the use of systemic enzyme therapy in this category of patients ensures rapid regression of the main clinical symptoms (on days 6-7), elimination of pathogenetic links of the disease more than in 90% of treated patients and the onset of remission for at least 6-12 months. It is characteristic that during the monotherapy with Wobenzim, positive results of treatment of generalized periodontitis were achieved, similar to those with the use of complex standard therapy, including administration of a number of medications with targeted action on pathogenesis mechanisms of the disease. From the position of evidence-based medicine, the expediency of replacing a broad arsenal of medicines in the complex treatment of generalized periodontitis with certain pharmacological preparations with a systemic effect is justified.
Authors and Affiliations
I. S. Mashchenko, T. O. Kucherenko
Keywords
Related Articles
- EP ID EP304355
- DOI 10.26641/2307-0404.2018.2.133947
- Views 95
- Downloads 0
Lyudmyla Mykolaivna Yur’yeva (the anniversary of birth)
The influence of intravenous solution «Neoreodez» on the course of experimental endotoxemia and evaluation of the regenerative properties of drug in the conditions of application
In the experiment it was shown that experimental endotoxemia induced by introduction of carbon tetrachloride and bacterial lipopolysaccharide is characterized by activation of free radical oxidation and failure of antiox...
Prognostic criteria for the development of infective endocarditis in children with heart pathology
To determine the most informative prognostic signs of infectious endocarditis development in children with heart pathology on the background of bacterial infections clinical course of 15 cases of infective endocarditis i...
Результати клінічної апробації фотодинамічної терапії в комплексному лікуванні гінгівіту, який ускладнює ортодонтичне лікування із застосуванням брекет-систем
Несмотря на высокую эффективность, применение брекет-систем у ортодонтических больных способно провоцировать развитие воспалительных процессов в тканях маргинального пародонта. Целью настоящего исследования стало изучен...
Ultrasonic duplex scanning as the standard for diagnostics of periphery arterial diseases of lower limbs in patients with diabetes mellitus in the development of purulent-necrotic complications
Diabetic foot or the syndrome of diabetic foot (SDF) is the problem due to a high frequency of ablations of the lower extremities followed with a significant social, psychological and economic consequences. The research...