Clinical assessment of anti-dengue IgM antibodies in suspected dengue cases in ANMMC, Gaya, Bihar
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 11
Abstract
Laboratory diagnosis of dengue virus infection is based mainly on serological tests. They are relatively inexpensive and easy to perform as compared to culture and nucleic acid based methods. In the primary infection, anti-dengue IgM antibodies are produced from fifth day of infection and remain in circulation for 60-90 days. Anti-dengue IgG antibodies are produced after one week, attain maximum after 2-3 weeks and remain lifelong in circulation. In secondary infection, IgG antibodies are detected at high levels in acute stage while IgM antibodies are present at low levels. The present study was conducted in Department of Microbiology, Anugrah Narayan Magadh Medical College (ANMMC), Gaya, Bihar, India. The 1350 patients suspected with dengue fever from October 2017 to September 2018 the study period of 12 months were included in the study. A single blood sample approximately 2-3 ml was collected from each patient in a plain vacutainer tube with all aseptic precautions. Serum was subjected to IgG and IgM anti dengue antibodies by dengue IgG capture enzyme linked immunosorbent assay (ELISA) and dengue IgM capture ELISA. From the present study it can be concluded that the serological prevalence of the dengue fever in the patients admitted to ANMMC Gaya is 7.41%. In the affected populations had majority of males and mid aged populations. The maximum cases are from monsoon season. This may be due to the increases breading of mosquitoes during the rains. Early diagnosis of infection can prevent life threatening complications and immunological assays such as the IgM capture ELISA is a reliable method for diagnosis of dengue virus infection.
Authors and Affiliations
Dr. Prem Prakash
Keywords
Related Articles
- EP ID EP587290
- DOI -
- Views 162
- Downloads 0
Assesment of Intestinal Obstruction in Children
Intestinal obstruction is one of the commonest surgical emergencies seen in pediatric patients. In last few decades, the scenario of diagnosis and management of pediatric intestinal obstruction has been changed due to be...
Quality Improvement initiative for Intravenous catheterization in NICU
Introduction: Intravenous (IV) therapy is an important and unavoidable part of therapy in NICU. Catheter related infections (CRI) were associated with IV therapy where we uses IV catheters. In the United States of Americ...
The study on clinical profile of patients with gallstones
Introduction:Cholelithiasis means the “presence of stone in the gall bladder” is a common clinical entity affecting the adult population of both sexes. Various sign and symptoms like severe pain in Murphy’s point in righ...
A comparative study of maternal and fetal outcome in trial of labour after caesarean section and elective repeat cesarean section
Background: Caesarean section is one of the commonest operations performed on childbearing women, with rates continuing to rise worldwide. Previous caesarean delivery is one of the most common indications for repeat caes...
A comparative study of early versus delayed emergency open appendectomy
Introduction: The controversy still exists about the timing of operation for appendicitis. The aim of this study was to compare the outcomes between early appendectomy and delayed appendectomy and assess the feasibility...