Clinical Assessment of the Autonomic Nervous System in Type 2 Diabetes Mellitus and Its Correlation with Glycemic Control, Duration and Microalbuminuria
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 8
Abstract
Abstract:The Clinical assessment of the autonomic nervous system in Diabetes mellitus (DM) and its correlation with glycemic control, duration and microalbuminuria, Cross sectional study of 96 adult diabetes patients. Ninety six patients with DM who were on regular treatment with either insulin and/or oral hypoglycemic agents were studied. Cardiovascular autonomic neuropathy (CAN) score was calculated using the clinical test variables. Of the 96 patients 45 had no CAN, 31 had early CAN and 20 had severe CAN. The mean HbA1C was 7.83.The mean of CAN score increased with duration of diabetes. The mean CAN score was higher in patients who had complication of diabetes as compared to patients without complications. The heart rate variability with respiration was found to be 15.84 ± 7.02/min. The mean valsalva ratio was 1.31 ± 0.23.The mean 30:15 ratio was 1.06 ± 0.04.The mean drop in BP on standing was 7.30 ± 7.24 mmHg. The mean rise in diastolic BP on sustained hand grip was 16.04 ± 4.11 mmHg. The prevalence of autonomic neuropathy in DM as assessed by CAN score was 45%.The CAN score did not correlate with the duration of DM. The HbA1C had a significant correlation with the severity of autonomic neuropathy. Occurrence of CAN correlated with the presence of peripheral neuropathy but not with the presence of retinopathy or nephropathy. All individual tests in the battery of CAN score were significantly associated with the presence of autonomic neuropathy, except 30:15 ratio. Keywords:Cardiovascular autonomic neuropathy, diabetes mellitus, heart rate variability, postural hypotension, valsalva ratio
Authors and Affiliations
Honnutagi RM, UdayBhanu C, Biradar MS
Keywords
Related Articles
- EP ID EP373125
- DOI -
- Views 65
- Downloads 0
Study of Suryanamaskar, Nadishodhana Pranayama, Omkar Chanting and Meditation (Yoga) on Respiratory Parameters in Young Healthy Medical Students
Stress may be defined as psychophysiological process usually experienced as a negative emotional state. It is a common condition, a response to a physical threat or psychological distress that generates a host of chemica...
To Correlate the Association of Markers of Chronic Renal Failure in Patients With and without Haemodialysis
Chronic kidney disease is a worldwide public health problem with an increasing incidence and prevalence, poor outcomes, and high cost. Outcomes of chronic kidney disease include not only kidney failure but also complicat...
Type 2 Diabetes Mellitus is associated with Arterial Stiffness in adult men of Western Rajasthan
Abstract:Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for cardiovascular disease (CVD) and mortality. By assessing the arterial stiffness in diabetics, the risk of CVD could b...
The Use of Chest Circumference as an Anthropometric Surrogate in Prediction of Low Birth Weight: The Port Harcourt Study
Low birth weight (Birth weight < 2,500g) has been identified as the single most important underlying factor for neonatal deaths. In Nigeria, 36% of deliveries happen at home, in churches or with traditional birth attenda...
Computer Simulation– A Future Perspective in Understanding the Concepts of Physiology
Computer simulation has contributed heavily in escalating our current knowledge of human physiology. A coalition of interconnected operations is known as system and a simulation model mimics the original system. The prim...