CLINICAL, CYTOLOGICAL AND HISTOPATHOLOGICAL CORRELATION IN LESIONS OF UTERINE CERVIX
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 64
Abstract
BACKGROUND Cytological screening of the uterine cervix by Papanicolaou test has reduced the incidence of cervical cancer. But cytological diagnosis in clinically suspicious lesions of cervix is provisional and has to be corroborated with histopathological findings for effective treatment response. MATERIALS AND METHODS Study Design- A descriptive study. Three hundred patients attending Gynaecological Oncology OPD of A.H. Regional Cancer Centre, Cuttack during the period April 2016-March 2017, were studied. History taking, clinical examination was followed by cervical smear and multiple punch biopsies, in patients with unhealthy cervix. The cytological and histopathological results were correlated with each other and clinically. RESULTS Clinically, cancer was detected in 77.6% cases. Cytologically, 73.3% reported carcinoma and 3.33% squamous intraepithelial lesions. Histopathologically, 74.6% showed carcinoma and 3.7% SIL. The cytohistopathological agreement was 69.2% in inflammatory lesions and 90.5% in invasive carcinomas. In clinically unhealthy cervix, a report of squamous intraepithelial-lesion by cytology was seen in 17.02% and by histopathology was found in 19.15%. Cytological proof of cancer was obtained in 73.3% of cases and histopathological proof in 74%. On overall analysis of 300 cases of suspicious cervix, 229 correlated well with cytology, labelling them as abnormal and 246 cases were stamped as diseased by histopathology. CONCLUSION This study proves that cytology can be used as a very effective screening tool to catch high risk cases, which can be biopsied to detect cancer early. Both cytology and histopathology correlate well with clinically obvious lesions of the cervix.
Authors and Affiliations
Jita Parija, Janmejaya Mohapatra
Keywords
Related Articles
- EP ID EP231484
- DOI 10.14260/Jemds/2017/1006
- Views 86
- Downloads 0
ASSESSMENT OF UMBILICAL CORD BLOOD IRON AND TIBC LEVELS IN NEONATES OF ANAEMIC MOTHERS
The most common cause of anaemia in pregnancy is Iron deficiency which can affect the newborns. This study was done to compare the serum Iron & Total Iron Binding Capacity (TIBC) levels in the 20 newborns...
STRESS DISTRIBUTION IN THE NASOMAXILLARY COMPLEX FOLLOWING APPLICATION OF ORTHOPAEDIC HEADGEAR FORCES- A 3-DIMENSIONAL FEM STUDY
BACKGROUND Extraoral force has been in use in orthodontics since Cellier introduced it in early 1800s. Like many other treatment modalities, interest in headgears and the understanding of its probable effect has varied o...
OCULAR MANIFESTATIONS OF HUMAN IMMUNODEFICIENCY VIRUS IN RELATION TO CD4 COUNT
[b] AIM[/b]: This study evaluates varied type of ocular manifestation associated with HIV/AIDS in co relation to CD4 count [b]METHODS[/b]: All patients with HIV/AIDS attending KIMS ART center between August 2008...
A RANDOMISED CONTROLLED TRIAL TO COMPARE THE EFFECTS OF TWO METHODS OF PREOPERATIVE HAIR REMOVAL ON SURGICAL SITE INFECTIONS IN PATIENTS UNDERGOING ELECTIVE TYMPANOPLASTY
BACKGROUND From time immemorial, ever since the principles of disinfection were being brought into being, it has been noticed that it is the seemingly simple and easy steps that brought giant breakthroughs in infection c...
CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ITS RISK FACTORS: A CASE CONTROL STUDY.
Chronic obstructive pulmonary disease (COPD) has been defined as a disease characterized by airflow limitation that is not fully reversible. It is a major health problem in India in terms of morbidity and morta...