Clinical Dementia Rating Scale (CDR) and dementia risk in the Mild Cognitive Impairment patients
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 10
Abstract
Introduction. Mild Cognitive Impairment (MCI) is a syndrome defined as cognitive decline greater than expected for an individual’s age and education level but that does not interfere notably with activities of daily life. The main criterion of MCI is memory impairment, and the most common method of diagnosis is Clinical Dementia Rating (CDR), scored in MCI as 0.5.Aim. We tried to estimate the utility of particular CDR’s boxes scores in dementia risk estimation.Material and methods. Boxes of CDR (Memory, Orientation, Judgment & Problem Solving, Community Affairs, Home & Hobbies, Personal Care) baseline scores of 103 MCI persons (mean age 69.32; 80 females and 23 males) were analyzed in 2 groups: non demented – ND (n = 80; mean age 68.71; 56 females and 24 males), and demented – D (n = 23; mean age 71.82; 14 females and 9 males) after 3-year follow up.Results. Any significant difference weren’t observed in Memory, Orientation and Judgment. The most differentiating were Community Affairs and Home & Hobbies, which were on favor in the non-demented group (p = 0.05).Conclusions. MCI subjects who later develop dementia differ from stable ones in functional domains of CDR at baseline evaluation. Analysis of particular CDR’s boxes scores might be helpful in further patients’ management.
Authors and Affiliations
Anna Barczak, Tomasz Gabryelewicz, Bogusław Wasiak, Maciej Golan, Małgorzata Chodakowska-Żebrowska, Maria Styczyńska, Monika Mandecka
Niedoczynność tarczycy a układ sercowo-naczyniowy
Hormony tarczycy działają na układ sercowo-naczyniowy poprzez genom, wpływając na syntezę białek kurczliwych serca, pompę wapniową, sodowo-potasową i fosfolamban oraz pozagenomowo, regulując aktywność kanałów jonowych w...
The obesity in kidney transplantation candidates – methods of treatment
The epidemic of morbid obesity is becoming more likely in patients with chronic kidney disease, worsening the control of comorbid conditions and total cardiovascular risk. Furthermore, it delays or makes the kidney trans...
Effects of amiodarone on the thyroid function
Amiodarone, a class III anti-arrhytmic agent, is a beznzofuran derivative containing 75 mg iodide per 200 mg tablet. During the metabolism of 200 mg of the drug approximately 6-8 mg of inorganic iodine is released into t...
Wpływ diety wzbogaconej w wielonienasycone kwasy tłuszczowe omega-3 na funkcję skurczową i morfologię lewej komory oraz na wewnątrzkomórkowy obieg Ca2+ i elektrofizjologię w sercu szczura
Wstęp. Wielonienasycone kwasy omega-3 (ω-3 WNKT) należą do grupy tzw. Niezbędnych kwasów tłuszczowych, których organizm ssaków nie może syntetyzować de novo i muszą być one dostarczane z pokarmem. Badania epidemiologiczn...
Cushing’s syndrome and diseases of cardiovascular system
Chronic hipercortisolism is characterized by a series of serious complications involving cardiovascular system. Population-based studies indicate that Cushing’s syndrome is associated with increased mortali...