Clinical evaluation of fibrinogen level in type II diabetes mellitus: A descriptive study from urban Karnataka
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 2
Abstract
Background: Diabetes mellitus comprises a group of common metabolic disorders where increased fibrinogen levels can act as a thrombogenic factor. Diabetic patients have higher cardiovascular morbidity than non-diabetic subjects. Several studies have shown that haemostatic factor especially hyper fibrinogenemia is implicated as a source of atherosclerosis and its complications. Objective: To assess the fibrinogen levels in patients of type-2 diabetes mellitus Methodology: This study included 100 cases of type-2 diabetes mellitus who attended the OPD at Government General Hospital and Basaveshwar Teaching and General Hospital, attached to Mahadevappa Rampure Medical College, Gulbarga in year 2005. Newly detected type-2 diabetic patients with and without associated hypertension of more than 40 years of age belonging to both sexes were included. Results: Maximum number of type-2 diabetic patients in the age group of 50– 59 years (39 patients, 39.9%). The sex distribution among the patient groups showed male preponderance with respect to each age group and as a whole. The correlation coefficient between age and fibrinogen level was 0.69 (p<0.001), which is highly significant. higher plasma fibrinogen levels in females compared to males (6.371.65 versus 5.941.43). negative correlation between fibrinogen level and duration of diabetes. Conclusion: Positive correlation observed between age and fibrinogen level. Females had significantly higher mean plasma fibrinogen levels compared to males. Negative correlation seen between fibrinogen level and duration of diabetes.
Authors and Affiliations
Chandrakala . , Venkatesh Amalappa Desai
Keywords
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- EP ID EP516525
- DOI 10.26611/10219216
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